# Wixbio > China Professional Animal Vaccine Exporter Patents Researchers Partner Institutes Who we are? WIXBIO Animal Vaccines We have strong vaccine development and production capacity. We can provide customized and export services --- ## Posts - [WixBio Delivers Avian Influenza H5+H9 Inactivated Vaccine to Vietnamese Customer](https://wx.wixbio.com/news/wixbio-delivers-avian-influenza-h5h9-inactivated-vaccine-to-vietnamese-customer/) - [African Customer Places Repeat Order for WixBio Coccidiosis Tetravalent Live Vaccine](https://wx.wixbio.com/news/african-customer-places-repeat-order-for-wixbio-coccidiosis-tetravalent-live-vaccine/) - [Why Do Vaccinated Pets Still Get Sick?](https://wx.wixbio.com/articles/dog/why-do-vaccinated-pets-still-get-sick/) - [WIXBIO Inactivated Mycoplasma synoviae and Mycoplasma gallisepticum Vaccine (MS+MG) – Prevention and Control Guidelines](https://wx.wixbio.com/articles/poultry/mycoplasma-synoviae-and-mycoplasma-gallisepticum-prevention-guidelines/) - [Safe Without “Adeno” — WIXBIO Adenovirus Series Products](https://wx.wixbio.com/articles/poultry/safe-without-adeno-wixbio-adenovirus-series-products/) - [WixBio Delivers Inactivated Vaccine for E. coli, Pasteurella, and Salmonella to Nigeria Ahead of Schedule](https://wx.wixbio.com/news/wixbio-delivers-inactivated-vaccine-for-e-coli-pasteurella-and-salmonella-to-nigeria-ahead-of-schedule/) - [H9N2 Avian Influenza: A Hidden Challenge for the Poultry Industry and Veterinary Institutions](https://wx.wixbio.com/articles/poultry/h9n2-avian-influenza-risks-and-challenges/) - [WixBio and Kazakhstan’s UNIVET Company Hold In-Depth Technical Exchange](https://wx.wixbio.com/news/wixbio-and-kazakhstans-univet-company-hold-in-depth-technical-exchange/) - [Infectious Bursal Disease Vaccine and Field Control Measures](https://wx.wixbio.com/articles/poultry/infectious-bursal-disease-vaccine-and-field-control-measures/) - [WixBio Delivers Customized Quadrivalent Vaccine to Turkey](https://wx.wixbio.com/news/wixbio-delivers-customized-quadrivalent-vaccine-to-turkey/) - [Biosecurity and Operational Protocols: A Dual Firewall for Poultry Vaccine Immunization](https://wx.wixbio.com/articles/poultry/biosecurity-and-operational-protocols/) - [Infectious Bursal Disease in Chickens: Progress in the Study of Variant Strains](https://wx.wixbio.com/articles/poultry/ibd-in-chickens-progress-variant-strains/) - [11,000 bottles of poultry vaccines sent to Iraq](https://wx.wixbio.com/news/11000-bottles-of-poultry-vaccines-sent-to-iraq/) - [Vietnamese customer re-orders customized avian influenza multiplex vaccine](https://wx.wixbio.com/news/vietnamese-customer-re-orders-customized-avian-influenza-multiplex-vaccine/) - [Guidelines for Poultry Sample Collection and Submission](https://wx.wixbio.com/articles/poultry/guidelines-for-poultry-sample-collection-and-submission/) - [Turkey Customer Re-orders Hexavalent Poultry Vaccine](https://wx.wixbio.com/news/turkey-customer-re-orders-hexavalent-poultry-vaccine/) - [Essential Vaccines for Goats and Sheep: A Comprehensive Guide to Livestock Health](https://wx.wixbio.com/articles/livestock/essential-vaccines-for-goats-and-sheep/) - [Vaccine Adjuvants: The Key to Boosting Immune Efficacy](https://wx.wixbio.com/articles/vaccine-adjuvants-the-key-to-boosting-immune-efficacy/) - [What Vaccines Do Cats Need Annually? The Ultimate 2025 Guide for Cat Owners](https://wx.wixbio.com/articles/cat/what-vaccines-do-cats-need-annually/) - [WIXBIO Signs Letter of Intent to Cooperate with Russian Customer](https://wx.wixbio.com/news/wixbio-signs-letter-of-intent-to-cooperate-with-russian-customer/) - [Proper Use and Storage of Poultry Vaccines: A Scientific Immunization Guide](https://wx.wixbio.com/articles/poultry/proper-use-and-storage-of-poultry-vaccines-guide/) - [Chicken Manure Health Guide: Five Colors Reveal Flock Health Crises](https://wx.wixbio.com/articles/poultry/chicken-manure-health-guide-five-colors-reveal-flock-health-crises/) - [WIXBIO Executives Attend China-Ethiopia International Science and Technology Cooperation Seminar](https://wx.wixbio.com/news/wixbio-attend-china-ethiopia-international-science/) - [Waterfowl Vaccination Methods and Immunization Schedule](https://wx.wixbio.com/articles/poultry/waterfowl-vaccination-methods-and-immunization-schedule/) - [Wixbio Visits Iran’s ICD Group, Reaches Partnership Consensus and Successfully Signs Agreement](https://wx.wixbio.com/news/wixbio-signs-contract-with-icd-iran/) - [WIXBIO Upgrades Services, Using GPS Temperature Trackers to Ensure Cold Chain Transport Quality](https://wx.wixbio.com/news/wixbio-ensures-transport-quality-with-gps-temperature-tracking/) - [Guide to Antibacterial and Anti-Mycoplasma Drugs for Livestock and Poultry](https://wx.wixbio.com/articles/livestock/guide-to-antibacterial-and-anti-mycoplasma-drugs-for-livestock-and-poultry/) - [Wixbio Ships 1000 Vials Custom IBH Triple Inactivated Vaccine to Iraq](https://wx.wixbio.com/news/1000-vials-custom-ibh-triple-inactivated-vaccine-to-iraq/) - [Wixbio Again Ships Mass Customized Vaccines to Turkey](https://wx.wixbio.com/news/wixbio-again-ships-mass-customized-vaccines-to-turkey/) - [6,000 Vials Avian Influenza (H5+H9) Inactivated Vaccine Shipped to Vietnam](https://wx.wixbio.com/news/6000-vials-avian-influenza-h5h9-inactivated-vaccine-shipped-to-vietnam/) - [Iraq customer visits Wixbio learning vaccine products and technology](https://wx.wixbio.com/news/iraq-customer-visits-wixbio-learning-vaccine-products-and-technology/) - [Custom Duck Adenovirus Inactivated Vaccine Shipped for Vietnam](https://wx.wixbio.com/news/custom-duck-adenovirus-inactivated-vaccine-shipped-for-vietnam/) - [WIXBIO Delivers 14,000 Vials of Poultry Vaccines to Iraqi Client](https://wx.wixbio.com/news/wixbio-delivers-14000-vials-of-poultry-vaccines-to-iraqi-client/) - [Custom Duck Eutherian (Reo) Inactivated Vaccine Shipped to Customer in Vietnam](https://wx.wixbio.com/news/custom-duck-eutherian-reo-inactivated-vaccine-shipped-to-customer-in-vietnam/) - [Watch Out for Egg Drop Syndrome](https://wx.wixbio.com/articles/poultry/watch-out-for-egg-drop-syndrome/) - [Role and Prevalence of the Bursa of Fabricius](https://wx.wixbio.com/articles/poultry/role-and-prevalence-of-the-bursa-of-fabricius/) - [WixBio Delivers AI Vaccines & Drugs to Vietnam Customers](https://wx.wixbio.com/news/wixbio-delivers-ai-vaccines-drugs-to-vietnam-customers/) - [Duck Tambucus virus disease flow regulation and prevention and control strategies](https://wx.wixbio.com/articles/poultry/duck-tambucus-virus-prevention-and-control/) - [Newcastle Disease Vaccine(Genotype VII)](https://wx.wixbio.com/articles/poultry/newcastle-disease-vaccinegenotype-vii/) - [Veterinary subunit vaccines have promising applications](https://wx.wixbio.com/articles/veterinary-subunit-vaccines-have-promising-applications/) - [How to use Gumboro vaccines? Best Guide](https://wx.wixbio.com/articles/poultry/how-to-use-gumboro-vaccines/) - [Infectious bronchitis disease in poultry](https://wx.wixbio.com/articles/poultry/infectious-bronchitis-disease-in-poultry/) - [Identification diagnosis and prevention and control of infectious coryza](https://wx.wixbio.com/articles/poultry/identification-diagnosis-and-prevention-and-control-of-infectious-coryza/) - [Virulent Newcastle Disease and Prevention Advice](https://wx.wixbio.com/articles/poultry/virulent-newcastle-disease-and-prevention-advice/) - [How to treat infectious coryza in chickens?](https://wx.wixbio.com/articles/poultry/treat-infectious-coryza-in-chickens/) - [Types of Vaccination in Poultry](https://wx.wixbio.com/articles/poultry/types-of-vaccination-in-poultry/) - [Can a vaccinated dog get rabies?](https://wx.wixbio.com/articles/dog/can-a-vaccinated-dog-get-rabies/) - [How to treat coccidiosis in chickens?](https://wx.wixbio.com/articles/poultry/how-to-treat-coccidiosis-in-chickens/) - [WixBio New Adenovirus Vaccine Shipped to Iraq](https://wx.wixbio.com/news/wixbio-new-adenovirus-vaccine-shipped-to-iraq/) - [Can Dog Annual Vaccinations Be Done During Dental Cleaning?](https://wx.wixbio.com/articles/dog/dog-annual-vaccinations-be-done-during-dental-cleaning/) - [What vaccines do dogs need for boarding?](https://wx.wixbio.com/articles/dog/what-vaccines-do-dogs-need-for-boarding/) - [Best Newcastle Disease Prevention, Treatment Guide](https://wx.wixbio.com/articles/poultry/newcastle-disease-prevention-treatment-guide/) - [Russian Company PHARMINDUSTRIA Visits WIXBIO](https://wx.wixbio.com/news/russian-company-pharmindustria-visits-wixbio/) - [Avian influenza in birds: transmission modes & symptoms](https://wx.wixbio.com/articles/poultry/spread-of-avian-influenza-in-birds/) - [Infectious Bursal Disease Control and Treatment Guidelines](https://wx.wixbio.com/articles/poultry/infectious-bursal-disease-control-and-treatment/) - [Infectious Coryza in Chickens: Symptoms, Treatment, Prevention, and Vaccination Guide](https://wx.wixbio.com/articles/poultry/infectious-coryza-in-chickens-guide/) - [2024 International Technical Symposium on Animal Medicine Industry](https://wx.wixbio.com/news/2024-international-technical-symposium-on-animal-medicine-industry/) - [2023 WIXBIO participates in Moscow Livestock Show](https://wx.wixbio.com/news/2023-moscow-livestock-show/) - [WIXBIO study visit to Vietnam and signing with CNC](https://wx.wixbio.com/news/wixbio-study-visit-to-vietnam-and-signing-with-cnc/) - [Can you spay a cat without vaccinations?](https://wx.wixbio.com/articles/cat-articles/can-you-spay-a-cat-without-vaccinations/) - [Swine flu vs. avian flu vaccine: does flu vaccine cover swine flu?](https://wx.wixbio.com/articles/livestock/does-flu-vaccine-cover-swine-flu/) - [Do indoor cats need to be vaccinated? Importance and types of vaccines](https://wx.wixbio.com/articles/cat-articles/do-indoor-cats-need-to-be-vaccinated-importance-and-types-of-vaccines/) - [Protect Your Pup: Key Dos and Don'ts After Dog Vaccination](https://wx.wixbio.com/articles/dog-articles/dos-and-donts-after-dog-vaccination/) - [Pakistani agents visit WIXBIO's vaccine and veterinary plants](https://wx.wixbio.com/news/pakistani-customer-visits-wixbio-animal-vaccine-factory/) - [Egyptian customer Dr Essam visits WIXBIO factory and institute](https://wx.wixbio.com/news/egyptian-customer-dr-essam-visits-wixbio/) - [Kenyan partner Atlantis Pharmaceuticals visits WIXBIO](https://wx.wixbio.com/news/kenyan-partner-atlantis-pharmaceuticals-visits-wixbio/) - [Iraqi customer Alaq, Al-Shaheen visits WIXBIO](https://wx.wixbio.com/news/iraqi-customer-alaq-visits-wixbio/) - [President of CNC Vietnam visited WIXBIO to deepen cooperation](https://wx.wixbio.com/news/president-of-cnc-vietnam-visited-wixbio/) - [Essential Guide to Leptospirosis in Dogs: Causes, Symptoms, Treatment, and Vaccination](https://wx.wixbio.com/news/guide-to-leptospirosis-in-dogs/) --- # # Detailed Content ## Posts On December 9, 2025, WixBio successfully delivered a shipment of bivalent inactivated avian influenza (H5+H9) vaccine to a customer in Vietnam. The shipment consisted of products in 250 mL and 500 mL packaging, and it filled one standard refrigerated container, which was dispatched via sea freight. This delivery represents a routine supply batch carefully organized by WixBio in accordance with Vietnamese market disease control requirements and the customer’s order schedule. Subtypes H5 and H9 of the avian influenza virus remain endemic in Southeast Asia and continue to pose a persistent threat to the poultry industry. The WixBio H5+H9 inactivated vaccine incorporates antigens matched to locally circulating field strains, providing effective immunogenicity and protective efficacy, and has gained broad acceptance in the Vietnamese market. To maintain product quality and stability during long-distance sea transport, the entire shipment was transported in a professional refrigerated container with temperature strictly controlled within the 2–8 °C range. Real-time temperature monitoring and recording devices were employed, enabling full traceability of temperature conditions from the manufacturing facility to the destination port, thereby ensuring optimal vaccine potency and efficacy. This full-container sea shipment demonstrates WixBio’s established capabilities in managing large-scale international logistics and underscores the company’s ongoing commitment to the strategically important Vietnamese market through efficient and reliable service. WixBio stated that it will continue to leverage its stable production capacity, precise strain-matching processes, and dependable global cold-chain logistics network to supply high-quality, timely animal health vaccines to customers worldwide, including Vietnam, thereby supporting the sustainable development of... --- On December 11, 2025, WixBio successfully fulfilled a repeat order from an African customer, supplying coccidiosis tetravalent live vaccine in the 1,000-dose presentation. The product has gained broad acceptance across Africa and Southeast Asia due to its consistent immunogenicity and field efficacy, serving as an important tool for coccidiosis control in broiler and breeder operations. Coccidiosis remains one of the most significant parasitic diseases affecting the global poultry industry, causing retarded growth, reduced feed conversion efficiency, and, in severe cases, elevated mortality. The WixBio tetravalent live vaccine incorporates four major pathogenic Eimeria species, inducing robust cross-protective immunity against locally prevalent field strains and substantially reducing the risk of clinical disease. This repeat purchase reflects the customer's confidence in the quality, immunogenic efficacy, and technical support provided by WixBio. To address varying regional disease patterns and regulatory requirements, WixBio maintains a customer-oriented approach by offering customized strain combinations, dosage forms, and packaging options while adhering strictly to international Good Manufacturing Practice (GMP) standards to ensure product safety and batch-to-batch consistency. For logistics and delivery, WixBio employs specialized cold-chain transportation protocols tailored to the temperature- and time-sensitive nature of live vaccines, maintaining product viability throughout the supply chain from manufacturing facility to end user. The head of WixBio's International Business Division stated, “The continued strong demand for our tetravalent coccidiosis live vaccine in Africa and Southeast Asia reflects our commitment to localized service and precise response to regional needs. Moving forward, we will further expand our product portfolio and enhance technical support... --- Vaccination is the cornerstone of preventive veterinary medicine, yet many owners are understandably frustrated when a fully vaccinated pet still contracts an infectious disease such as canine parvovirus, feline panleukopenia, or rabies. This article, based on current peer-reviewed literature and extensive clinical experience, explains the three most common reasons for apparent vaccine failure and provides practical, science-based recommendations to maximize protection. Vaccines are highly effective but not 100 % foolproof Real-world protection rates for core pet vaccines typically range from 80–95 %, and the World Organisation for Animal Health (OIE) estimates that approximately 30 % of reported “vaccine failures” actually reflect unrealistic owner expectations rather than true product failure. The Three Principal Causes of Vaccine Failure Antigenic Drift and Strain Mismatch: Viruses evolve Canine parvovirus (CPV) has mutated from the original CPV-2 (1978) into globally dominant variants CPV-2a, 2b, and 2c. Older vaccines formulated only with the original strain may provide reduced cross-protection ( 40 % of clinical CPV cases worldwide. Recommendation: Use modern multivalent vaccines that include updated CPV-2b/2c field strains and perform annual antibody titer testing (protective threshold by ELISA ≥1:16). Host-Related Immune Response Failure Not every animal mounts an adequate response. Maternal antibody interference: Puppies and kittens receive high levels of passive immunity via colostrum (titers may exceed 1:512). These antibodies neutralize vaccine antigen and create an immunological “gap” typically between 6 and 16 weeks of age. Immunosenescence and comorbidity: Senior pets, animals with chronic kidney disease, malnutrition, or concurrent illness often exhibit seroconversion rates as low... --- Mycoplasma synoviae (MS) and Mycoplasma gallisepticum (MG) are major avian pathogens severely impacting poultry health and productivity. According to recent data, MS+MG co-infection rates in commercial flocks exceed 40%, leading to significant economic losses. The WIXBIO Inactivated MS+MG Vaccine is formulated with dual inactivated strains and an oil adjuvant to provide broad-spectrum, long-term protection against both pathogens. This guideline draws on evidence from major publications within the last 5 years and the biological features of MS and MG to present optimal vaccination strategies. It also outlines recommended immunization schedules and integrated control measures for precise immunization and effective prevention of recurrence. Pathogen Characteristics and Current Epidemiology Pathogen Profile MS: Highly adept at establishing latent infections; colonizes the respiratory mucosa and disseminates hematogenously to joints, liver, spleen, and reproductive tract. Resistance to tylosin exceeds 70%. MG: Primarily induces respiratory disease; readily transmitted horizontally; long incubation period (2–4 weeks); resistant to heat and low pH. Co-infection: Synergistic pathogenesis markedly exacerbates arthritis; PCR surveys indicate co-infection rates >50% in affected flocks. In 2025, surveillance in central and eastern China found that positivity rates for MS+MG in broilers and layers continue to rise. Recurrence rates now reach 30%, driven mostly by circulating resistant strains and inadequate biosecurity. Clinical impacts include lameness, synovial effusion, a 10–20% drop in egg production, and a 5–10% increase in deaths from secondary Escherichia coli infections. Primary Causes of Recurrence and Rationale for Vaccination Persistent latent infection: Antibiotics fail to eliminate respiratory colonization (carrier rate >30%). Vaccination stimulates mucosal sIgA... --- Fowl adenovirus (FAdV) infection poses a significant threat to poultry production, causing inclusion body hepatitis (IBH) and hydropericardium syndrome (HPS), resulting in high mortality and economic losses. The WIXBIO adenovirus series utilizes advanced cell suspension culture technology and recombinant Fiber-2 protein expression to provide broad-spectrum, safe, and effective protection. This document outlines FAdV etiology, epidemiology, control measures, and WIXBIO product characteristics to support adenovirus-free poultry production. Etiological Characteristics of FAdV FAdV belongs to the genus Aviadenovirus in the family Adenoviridae. The virion is non-enveloped, 70–90 nm in diameter, and icosahedral. The capsid comprises 252 capsomers (240 hexons and 12 pentons), each with two fiber protrusions. The core contains double-stranded DNA (60–65 nm) and nucleoproteins. Resistance: Resistant to ether, chloroform, trypsin, and lipid solvents. Stable at pH 3–9; survives 60°C for 30 minutes or 50°C for 2 hours. Remains viable at room temperature for 6 months; inactivated by boiling for 5 minutes or 1:1000 formaldehyde. Serological Classification and Clinical Signs HostGenus/SpeciesSerotypePrimary Clinical SyndromeChickenAviadenovirus AFAdV-1Inclusion body hepatitis (IBH)Aviadenovirus BFAdV-5IBHAviadenovirus CFAdV-4, FAdV-10Hydropericardium syndrome (HPS)Aviadenovirus DFAdV-2, 3, 9, 11IBHAviadenovirus EFAdV-6, 7, 8a, 8bIBHGooseGoose AviadenovirusGoAdV-1, 2, 3–DuckUnclassifiedDAdV-2Duck white liver diseasePigeonPiAdV-1––TurkeyTAdV-1, 2––ParrotPsAdV-1, 2–– Prevalent strains: Group I, primarily FAdV-C4, E8b, and D11. Gross lesions: HPS: Pericardial effusion >5 mL, enlarged liver (rounded edges, hemorrhage, jaundice), enlarged kidneys (hemorrhage, jaundice), hemorrhage at proventriculus-gizzard junction. IBH: Enlarged, jaundiced, hemorrhagic liver with multiple necrotic foci; friable texture. General Control Measures Introduction management: Source chicks from FAdV-negative breeder flocks; implement strict all-in/all-out systems to prevent vertical transmission. Biosecurity: Thorough cleaning... --- On September 28, 2025, WixBio successfully fulfilled a critical air shipment order to Lagos, Nigeria, delivering 130 units of inactivated vaccines for poultry and livestock ahead of schedule. The shipment comprised 500ml bivalent inactivated vaccines for Escherichia coli and Pasteurella, and 500ml inactivated Salmonella vaccines. The consignment was transported via a fully monitored cold-chain air logistics system to ensure timely and secure delivery to the African market. This order was tailored to address the prevention needs of prevalent bacterial diseases in Nigeria’s poultry and livestock industries. Escherichia coli, Pasteurella, and Salmonella infections are significant bacterial diseases that contribute to high mortality rates, reduced egg production, and impaired growth in animals. Leveraging customer feedback and data on locally circulating bacterial strains, WixBio optimized the antigen formulation to provide broad-spectrum protection and robust immune efficacy. To maintain product quality and biological activity, all vaccines were produced, tested, packaged, and transported in strict compliance with Good Manufacturing Practice (GMP) standards. The vaccines were packaged in professional cold-chain containers equipped with temperature recorders, ensuring continuous temperature control (2-8°C) from the manufacturing facility to the airport and final destination, thereby preserving vaccine potency. Despite a constrained delivery timeline, WixBio’s production and logistics teams demonstrated exceptional coordination and efficiency. By optimizing production schedules and expediting release testing, the company achieved early delivery, underscoring its ability to respond swiftly and effectively to international market demands. The Nigerian client expressed high satisfaction with the product quality, packaging standards, and expedited delivery. They stated: “WixBio delivers stable and effective... --- Introduction: Low Pathogenicity Does Not Equate to Low Risk The H9N2 subtype of avian influenza virus has become widely prevalent in poultry populations across Asia, the Middle East, and Africa in recent years. Classified as a low-pathogenic avian influenza virus (LPAIV), H9N2 typically does not cause immediate large-scale mortality. However, it remains one of the most significant long-term threats to the poultry industry due to its persistent impact. The effects of H9N2 extend beyond reduced egg production, decreased feed conversion efficiency, and elevated mortality rates. Its ability to transmit across species and potential for genetic reassortment with highly pathogenic influenza strains pose substantial risks. Neglecting H9N2 not only threatens economic viability but also presents a latent public health concern. Risks to Poultry Farms Reduced Production Performance H9N2 infections frequently result in decreased egg production and compromised eggshell quality, directly reducing commercial value. In broiler poultry, H9N2 leads to slower weight gain and reduced feed conversion efficiency, increasing production costs. Complex Disease Management While H9N2 has a relatively low mortality rate, it significantly heightens the risk of secondary respiratory infections. These infections often occur concurrently with pathogens such as Newcastle disease virus, Mycoplasma spp. , or Escherichia coli, resulting in exacerbated losses. Vaccine Pressure and Antigenic Drift Although multiple avian influenza vaccines are available, the continuous antigenic drift of H9N2 may reduce vaccine efficacy, necessitating frequent updates to immunization protocols. Challenges for Veterinary Institutions and Public Health Zoonotic Potential Human infections with H9N2 are typically mild but may progress to severe... --- Nanjing, China, September 2025 — WixBio’s Overseas Business and Technical Departments recently hosted a face-to-face technical exchange meeting in Nanjing with representatives from UNIVET, a partner company from Kazakhstan. The discussions focused on critical technical aspects, including testing methodologies for poultry vaccines, epidemiological compatibility of vaccine strain subtypes, and adaptability to regional conditions. The meeting aimed to optimize the performance of WixBio’s vaccine products in the Central Asian market, ensuring consistent and effective immune protection across diverse climatic and farming environments. WixBio’s technical team provided a detailed overview of the company’s processes and quality control standards for vaccine antigen preparation, potency testing, specific pathogen-free (SPF) chicken embryo virus titration, and hemagglutination inhibition (HI) antibody monitoring. Additionally, they outlined the company’s approach to strain selection and updates based on country-specific epidemiological data. Given the recent prevalence of avian influenza (H9N2), Newcastle disease (G-7 strain), and infectious bronchitis in Kazakhstan, both parties thoroughly evaluated the compatibility of existing vaccine combinations. They also reached a preliminary agreement on the future development of customized multivalent vaccines. WixBio highlighted its robust customization capabilities, enabling rapid adjustments to vaccine formulations to deliver tailored disease prevention strategies, aligning with a “one country, one strategy; one region, one solution” approach. UNIVET representatives commended WixBio’s technical expertise and responsiveness, stating, “This in-depth exchange has strengthened our confidence in a long-term partnership with WixBio. Their products have demonstrated outstanding immunogenicity and stability in Kazakhstan, earning widespread approval from local farmers and regulatory authorities. ” This Nanjing meeting not only reinforced... --- Infectious bursal disease (IBD) in chickens, caused by infectious bursal disease virus (IBDV), is an acute, contact-transmissible disease primarily affecting 3- to 6-week-old chicks, leading to severe immunosuppression. In recent years, novel variant IBDV strains (nVarIBDV) have become widespread in China, with traditional vaccines showing limited efficacy. Based on 2025 surveillance data (from Qingdao Yibang Assurance Center and other institutions), WIXBIO addresses the “variable” (variant strain prevalence) and “constant” (environmental resistance, early infection risks) characteristics of IBDV, presenting comprehensive vaccine immunization and field control strategies, recommending the WIXBIO Trivalent IBD Vaccine to establish an effective control system. 1. IBDV Characteristics Analysis 1. 1 Variable: Viral Evolution Trends Evolutionary History: Evolved from classic virulent strains and very virulent IBDV (vvIBDV) to the currently dominant novel variant strains (nVarIBDV, A2dB1 genotype) and a minority of classic strains. 2025 Prevalence: Increased IBDV detection rates in white-feather broilers, young breeder chickens, and layer flocks, reported across 15 provinces (Northeast, East, and South China), with disease onset expanding to 15-35 days of age. Clinical Changes: Variant strains exhibit milder symptoms (primarily bursal swelling or atrophy) but induce more severe immunosuppression, reducing the efficacy of H5/H7 avian influenza and Newcastle disease vaccines by 30-40%. 1. 2 Constant: Environmental Resistance and Risks Resistance: Non-enveloped virus, highly resistant to pH 2, 50°C heat, and disinfectants (e. g. , quaternary ammonium compounds), surviving in poultry houses for up to 4 months. Early Infection Risks: Earlier infections (especially 70 μW/cm²). Environmental Optimization: Maintain poultry house ventilation (ammonia level --- WixBio recently supplied 2,000 bottles of 500ml quadrivalent inactivated vaccine for Newcastle Disease (ND), Infectious Bronchitis (IB), Avian Influenza (H9), and Fowl Adenovirus (FADV) to a Turkish client. This product was custom-developed to meet the client’s specific requirements and align with the characteristics of local epidemic strains, showcasing WixBio’s expertise in vaccine research, precise strain matching, and efficient delivery. The quadrivalent inactivated vaccine incorporates key antigenic components targeting prevalent poultry diseases in the region. Vaccine seeds were selected to match current epidemic strains, ensuring robust immune protection and broad cross-protection. Developed and manufactured under strict Good Manufacturing Practice (GMP) standards, the vaccine underwent rigorous multi-stage quality control to guarantee batch consistency, high potency, and safety. To meet the client’s stringent requirements for product quality, packaging, and delivery timelines, WixBio streamlined operations across production scheduling, quality release, and cold-chain logistics. A fully temperature-controlled transport system maintained the vaccine at a temperature range of 2–8°C throughout the supply chain, preserving its biological activity. Client feedback highlighted: “This tailored vaccine closely aligns with local epidemic strains and demonstrates exceptional performance in immune efficacy, antibody persistence, and safety, significantly improving the economic outcomes for our end users. ” This collaboration underscores WixBio’s commitment to a “customer-centric, science-driven” approach. The company remains dedicated to expanding its global presence, leveraging advanced customized R&D capabilities and a robust international supply chain to deliver precise, reliable, and efficient animal health solutions to partners worldwide. --- Vaccination is central to poultry disease control, with biosecurity and operational protocols serving as dual pillars to ensure vaccine efficacy and farm safety. Proper storage, pre-warming, administration, and quality assessment significantly enhance protection rates, while lapses in biosecurity or procedural errors can lead to vaccine failure and disease spread. WIXBIO, addressing poultry disease control needs (e. g. , Infectious Bursal Disease, IBD), provides standardized guidelines and inspection criteria to minimize non-conformance rates (target 70 μW/cm²). Luggage is disinfected in a gatehouse room using 30-minute UV irradiation or 0. 2% peracetic acid spray. Environmental Control: Perform vaccinations in negative-pressure or well-ventilated areas, maintaining ammonia levels --- Infectious Bursal Disease (IBD) in chickens is an acute, highly contagious, mainly immunosuppressive disease caused by Infectious Bursal Disease Virus (IBDV), which has caused significant economic losses to the global poultry industry. In recent years, a new mutant strain (nVarIBDV) has been found to be widely prevalent in China, exhibiting different antigenicity and pathogenicity from the traditional super virulent strain (vvIBDV), with limited protection by traditional vaccines. Based on the latest research, this paper systematically summarizes the epidemiology, antigenic changes, VP2 gene sequence analysis, and preventive and control measures of IBDV variant strains in China, which provides a scientific basis for effective control of the disease. Overview of Infectious Bursal Disease (IBD) Infectious Bursal Disease Virus (IBDV), from the Birnaviridae family, genus Avibirnavirus, has a genome comprising two double-stranded RNA segments, A and B: Segment A: Encodes VP2, VP3, VP4, and VP5. VP2, the primary capsid protein and protective antigen, is critical for viral virulence, cell tropism, and antigenic variation. Its hypervariable region (HVR, amino acids 206–350) is essential for genetic evolution studies. Segment B: Encodes VP1, an RNA-dependent RNA polymerase (RdRp), influencing viral replication and genetic evolution. IBDV is classified into two serotypes: Serotype I: Pathogenic to chickens, encompassing classical (cIBDV), variant (vaIBDV), very virulent (vvIBDV), and attenuated (atIBDV) strains. Serotype II: Primarily infects turkeys, non-pathogenic to chickens. IBD primarily affects chicks aged 3–6 weeks, targeting B lymphocytes in the bursa of Fabricius, resulting in severe immunosuppression, increased susceptibility to secondary infections, and reduced efficacy of other vaccines (e.... --- On July 28, 2025, in Beijing, China, WixBio completed another delivery of 11,000 vials of customized poultry vaccine to clients in Iraq. Building on trust in product quality and consistent market acclaim, Iraqi clients reordered 10,500 vials of the 500ml Newcastle Disease (ND), Avian Influenza (AI), and Fowl Adenovirus (FADV) triple-inactivated vaccine (referred to as “ND-AI-FADV inactivated vaccine”). This order underscores the strong recognition of WixBio’s products and their established reputation in the Iraqi market. Specifically formulated for poultry disease patterns in the Middle East, this ND-AI-FADV inactivated vaccine provides robust and broad-spectrum protection. Each batch undergoes rigorous quality control testing to ensure consistent immunogenicity and high protective efficacy. Feedback from Iraqi clients confirms that the vaccine significantly elevates poultry antibody titers and effectively reduces disease incidence, earning widespread praise from local farmers and veterinary professionals. To maintain vaccine potency and integrity during transport, WixBio implements a comprehensive cold-chain logistics system, supported by GPS temperature monitoring, ensuring every vial arrives in optimal condition. WixBio’s Head of Overseas Sales commented: “We are delighted by the continued confidence and support from our Iraqi clients. This order reflects not only the quality of our products but also our commitment to delivering superior animal health solutions worldwide. ” This successful order strengthens WixBio’s foothold in the Middle East market, highlighting its dedication and capability to expand globally. Moving forward, WixBio will continue to advance research and development, as well as technical innovation, to provide high-quality, reliable animal health products to more countries and regions. --- On July 24, 2025, in Zhengzhou, China, based on the local avian influenza epidemic situation in Vietnam, WixBio tailored an avian influenza H5 (N6+N8)+H9N2+Newcastle Disease (ND, G-7 strain) multivalent inactivated vaccine for the Vietnamese market. This vaccine, due to its excellent antibody levels and clinical protection rate after primary and secondary immunizations, has once again received bulk orders from Vietnamese customers, earning high praise. This customized vaccine is precisely matched to the currently circulating avian influenza virus strains in Vietnam, covering the H5 subtype (N6 and N8 strains), H9N2 subtype, and Newcastle Disease G-7 strain, with good cross-protection capability and immunogenicity. Customer feedback indicates that after vaccination, the antibody titers in poultry flocks rise rapidly, providing significant immune protection that effectively controls the risk of avian influenza transmission and significantly reduces mortality and economic losses. WixBio consistently adheres to a customer-centric and market-demand-oriented research and service philosophy, continuously optimizing vaccine strain matching technology to enhance product applicability and effectiveness under different regional and epidemic trends. This high recognition from Vietnamese customers once again proves the company’s professional strength and market responsiveness in the animal vaccine field. To ensure vaccine quality and transportation safety, WixBio adopts a comprehensive cold-chain transportation solution, ensuring the vaccine reaches customers in optimal condition and guarantees unaffected immunization effects. WixBio states that in the future, it will continue to strengthen cooperation with Vietnam and other overseas markets, conduct in-depth studies on local disease epidemic trends, and provide more precise and efficient vaccine solutions to support the... --- Poultry diseases often present as mixed or secondary infections, characterized by clinical symptoms and necropsy findings that can lead to misdiagnosis. Lab-based pathogen detection is key to getting it right. The sampling site, storage method, and transport conditions directly affect test accuracy. This guide covers the essentials for collecting and submitting poultry samples, with a focus on diseases such as Infectious Bursal Disease (IBD), offering practical tips to enhance pathogen detection and diagnostic efficiency. Basic Principles of Sample Collection Choosing Representative Samples Goal: Pick moribund or recently deceased ( --- On July 15, 2025, in Zhengzhou, China, WixBio fulfilled a repeat order from a Turkish client, shipping 4,000 bottles of 500ml inactivated hexavalent vaccine (a six-in-one shot) for Newcastle Disease (ND-G7 strain), Avian Influenza H9 subtype (H9), and Duck Adenovirus types 4, 8, and 11 (FADV-4, FADV-8, FADV-11). The vaccines were shipped via a complete cold-chain system to Turkey, ensuring safe and timely delivery. This order demonstrates the high value our Turkish client places on WixBio’s products, reflecting their trust in our quality, packaging, and prompt delivery. Since using the initial batches, they’ve reported an excellent immune response, high antibody levels, and broad protection, receiving great feedback from local farms and veterinary clinics. This hexavalent vaccine is a tailored formula designed to tackle common poultry diseases in Turkey, effectively preventing Newcastle Disease, Avian Influenza, and multiple serotypes of Duck Adenovirus infections, significantly cutting down morbidity and mortality while boosting farm efficiency. To maintain the vaccine's full activity during transport, WixBio utilized a comprehensive cold-chain system with GPS temperature monitoring, ensuring seamless management from the factory to the client and maintaining reliable vaccine quality. The head of WixBio’s Overseas Business Division said: “We’re truly grateful for our Turkish client’s ongoing trust and support. Every repeat order proves the strength of our products and services. We’ll keep pushing high standards to deliver top-notch animal health solutions worldwide. ” This shipment further solidifies WixBio’s presence in the Turkish market and highlights our growing expertise in international customized vaccine supply and cold-chain logistics. About... --- Raising healthy goats and sheep requires more than just good feed and shelter—a bright vaccination plan is one of the most effective ways to prevent disease outbreaks and save money. In this article, WIXBIO addresses livestock owners' top questions about goat and sheep vaccinations, offering practical tips on essential vaccines and when to administer them. Why Must Goats and Sheep Be Vaccinated? Goats and sheep can easily contract infectious diseases, especially in large farms or areas where animals frequently move. Many of these diseases spread fast and can be deadly. Vaccines help animals fight off harmful germs before they get sick. Preventing disease is always cheaper than treating it. Core Vaccines for Goats and Sheep Vaccines are categorized into essential vaccines (required for all animals) and non-core vaccines (selected based on local risks or farm conditions). Below are the key vaccines for goats and sheep, answering the main questions and keeping things clear for B2B clients. Core Vaccines for Goats Goats are prone to several infectious diseases, but vaccines can keep them safe. Here are the must-have vaccines: Clostridium C & D + Tetanus Vaccine (CDT Vaccine)Purpose: Protects against enterotoxemia (overeating disease) caused by Clostridium perfringens types C and D and tetanus caused by Clostridium tetani. Importance: Diet changes can cause enterotoxemia, while wounds or birthing can lead to tetanus. Schedule: Goat kids get their first dose at 6-8 weeks, followed by a booster 4 weeks later. Adults need an annual shot. Pregnant does should be vaccinated 4-6 weeks before... --- Vaccines are the cornerstone of infectious disease prevention, triggering innate immunity and stimulating antigen-presenting cells (APCs) to induce adaptive immune responses against specific pathogens. Adjuvants, as critical vaccine additives, significantly enhance vaccine effectiveness by amplifying, modulating, and prolonging immune responses. WIXBIO explores the history, mechanisms, types, applications, and latest advancements in vaccine adjuvants, combining real-world cases from human and veterinary vaccines to provide scientific guidance for development and use. 1. History of Vaccine Adjuvants Adjuvant research began in the early 20th century to address the low immunogenicity of early purified antigens. Key milestones include: 1920s: Aluminum salts (aluminum hydroxide, aluminum phosphate) became the first human vaccine adjuvants, used in diphtheria and tetanus vaccines, laying the foundation for adjuvant use. They are also widely used in veterinary vaccines, such as inactivated avian influenza vaccines. 1990s: Oil-in-water emulsion adjuvants (e. g. , MF59) emerged for human influenza vaccines (e. g. , Fluad) and veterinary Newcastle disease vaccines, enabling the slow release of antigen and innate immune activation. 2000s: Novel adjuvants like AS03 (squalene + α-tocopherol) and AS01 (liposomes + monophosphoryl lipid A) were approved for human H1N1 influenza, malaria (RTS, S), and shingles (Shingrix) vaccines, as well as veterinary swine fever vaccines. 2010s–Present: TLR9 agonists (e. g. , CpG-1018) were approved for human hepatitis B vaccines (Heplisav-B) and veterinary foot-and-mouth disease (FMD) vaccines, with nanotechnology and molecular biology driving the development of adjuvants. Challenges: Aluminum salts, used for over 70 years, aren’t fully understood; novel adjuvants require further safety and tolerability validation,... --- As a cat owner, you want your furry friend to stay healthy and happy, sharing countless cozy moments with you. Vaccines are a key defense against serious diseases. But questions like “What vaccines do cats need every year? ” or “Do indoor cats need shots? ” can be confusing. Wixbio is here with clear, practical advice to help you create the best cat vaccine plan for your cat. As a leading animal vaccine supplier and exporter, Wixbio is committed to providing high-quality vaccines to ensure reliable protection for your cat. Let’s build a healthy future for your feline friend! Understanding Cat Vaccines Vaccines act like a protective shield, guarding cats against highly contagious, potentially deadly diseases. They come in two types: core vaccines (essential for every cat) and non-core vaccines (chosen based on lifestyle). Knowing what each vaccine does helps you and your vet pick the proper protection plan. Core Vaccines: Must-Haves for Every Cat Core vaccines are essential for every cat, whether they’re indoor cuddle bugs or outdoor adventurers. These target widespread, high-risk diseases. FVRCP Vaccine (Triple Vaccine): One shot protects against three diseases: Feline Viral Rhinotracheitis: A respiratory illness causing sneezing, watery eyes, and fever. Feline Calicivirus: A respiratory virus leading to mouth ulcers or lameness. Feline Panleukopenia: A severe, often fatal virus attacking the digestive system. Frequency: Kittens start at 6-8 weeks, with boosters every 3-4 weeks until 16-20 weeks. Adult indoor cats typically need boosters every 3 years; outdoor or high-risk cats may need annual shots.... --- Recently, Mr. Fang Fangshuo, a key partner from Russia, accompanied by translator Ms. Zhang, visited WixBio for detailed discussions on product customization and technical cooperation, ending with a signed letter of intent to collaborate. This visit marks a major step in strengthening their animal health partnership and sets the stage for closer future collaboration. During the visit, Mr. Fang explored WixBio’s R&D capabilities, production facilities, and quality control systems in depth. Both sides had detailed discussions on tailoring products to meet the Russian market’s specific needs, focusing on the suitability and market potential of vaccines for avian influenza and Newcastle disease. Technical cooperation was also a major focus, covering advancements in vaccine technology, production process improvements, and potential future collaboration models. WixBio showed off its state-of-the-art production equipment and strict quality management system, highlighting its ongoing commitment to product quality and safety. The two parties also discussed boosting product competitiveness through technology transfer and joint R&D to address the diverse needs of customers across different regions. After a series of productive talks, WixBio and Mr. Fang agreed on a wide range of cooperative efforts and formally signed the letter of intent. This agreement spans multiple areas of collaboration, aiming to combine their strengths to advance the animal health industry. WixBio stated: “We’re thrilled about this partnership with our Russian colleagues. It’s not just a nod to our technology and products but also a big step toward sustainable growth of global livestock farming. We’ll keep providing top-quality, efficient services and support... --- Vaccines are essential for preventing poultry diseases, but improper use or storage often leads to immunization failures and financial losses. According to Weikesi Biotech's field studies, issues such as oil emulsion breakdown and injection site swelling typically result from poor storage or incorrect handling. This guide, grounded in veterinary research and clinical experience, details proper methods for using and storing poultry vaccines to help farmers achieve adequate immunization. Choosing the Right Vaccination Method Different vaccines require specific delivery methods for optimal results. Below are common vaccines and their recommended delivery methods: Vaccine TypeRecommended MethodNotesInfectious Bronchitis Live Vaccine (H120)Eye drop, nasal drop, sprayStimulates respiratory mucosal immunityInfectious Bursal Disease Live Vaccine (CF/B87/CA strain)Drinking waterIdeal for large flocks, easy to administerNewcastle Disease Inactivated VaccineInjectionRequires precise dosing, suitable for older chickens Note: Always follow the vaccine's instructions. Incorrect methods may weaken or nullify the immune system's effectiveness. Standard Procedures for Key Vaccination Methods Eye Drop Vaccination Used For: Respiratory disease vaccines (e. g. , infectious bronchitis, Newcastle disease live vaccines), stimulating the eye gland for local and systemic immunity. Key Steps: Dose Control: Ensure precise dosing—30ml of diluent should vaccinate 1,000 birds. Test by dripping 3 mL of diluent 100 times; if the diluent is used up, the dropper size is correct. Adjust the dropper or bottle pressure if there is an excess or shortage of liquid. Technique: Hold the dropper 1cm from the eye, administer one drop, and gently rub it to distribute evenly. Standard Issue: Too small a dose leads to insufficient... --- Chicken manure is a “barometer” of flock health. By examining its color, shape, and texture, farmers can quickly identify potential diseases and implement targeted prevention and control measures. This guide, based on veterinary research and practical experience, breaks down the health signals in chicken manure and offers science-backed diagnostic and management solutions. Characteristics of Normal Chicken Manure Healthy chicken manure shows a flock’s good physical condition. Here’s how normal manure should look: Shape: Regular cylindrical, 1-2 cm in diameter, formed but not overly complicated. Texture: Slightly dry exterior, containing feed particles, with a white urate coating. Color: Grayish-brown base with a white “frost” (urate crystals). Composition: About 65% water, 25% feed residue, 10% microbes and their metabolites. Odor: No strong, pungent smell, slightly fermented. Tip: Normal manure pH is typically 6. 5-7. 5, showing healthy digestion and metabolism. Five-Color Warning System: Health Signals Behind Manure Colors Changes in manure color often signal early disease. Below are five abnormal colors, their causes, diagnoses, and management plans: Green Manure: Liver and Gallbladder Issues Pathological Mechanisms: Bilirubin Metabolism Issues: Viral hepatitis (e. g. , Newcastle disease) or liver cell damage causes biliverdin reflux. Intestinal Infections: Infections with Salmonella or Trichomonas disrupt the enterohepatic cycle, leading to increased β-glucuronidase activity. Clinical Types: TypeColor FeaturesTypical DiseaseDiagnostic IndicatorsVaccine StressLight green streaksNewcastle disease vaccine stressHI antibody titer ≥4log2Viral PrecursorYellow-green, formedEarly low-pathogenic avian influenzaH5/H7 antigen rapid test positiveSepticemiaDark green, wateryAcute Pasteurella infectionBlood culture positive rate >90%ParasiticInky green, mucoidTrichomonas infectionCecal content microscopy detects parasites Management Plan: Liver Support: Add... --- May 30, 2025, Binzhou, Shandong — Senior representatives from WIXBIO were invited to the “2025 High-Level Foreign Experts Qilu Tour and China-Ethiopia International Science and Technology Cooperation Seminar” in Binzhou, Shandong. The conference focused on promoting China-Africa scientific and technological cooperation in zoonotic disease prevention, with a particular emphasis on the need and feasibility of establishing a “China-Africa Joint Laboratory for Zoonotic Diseases. ” During the event, the Ethiopian expert delegation visited the Binzhou Key Laboratory for Zoonotic Diseases, where they learned about the lab’s technical capabilities and research achievements in pathogen detection, vaccine development, and epidemic surveillance. As a leading enterprise in veterinary biologics, WIXBIO actively participates in discussions on key topics and shares its role and potential in technology transfer, product development, and international cooperation. Through in-depth exchanges, both sides reached an critical consensus on cooperation in these areas: Joint Laboratory Establishment: Establish a China-Africa joint laboratory to address the prevention needs of zoonotic diseases, thereby enhancing disease surveillance and control in Africa. Joint Research Initiatives: Combine Chinese technology with Ethiopian local epidemiological data to develop vaccines and diagnostic technologies tailored for Africa. Talent Development and Technical Training: Help Africa train local professionals through joint programs and technical support. Technology Transfer and Innovation Cooperation: Promote the transfer of advanced technologies in vaccine production, quality control, and cold chain logistics to Africa. Institutionalized Academic and Scientific Exchange: Establish a regular academic exchange platform to promote information sharing and exchange of research results. WIXBIO executives said: “We’re thrilled to join... --- Vaccinating waterfowl, like ducks and geese, is key to preventing infectious diseases. Choosing the right vaccines and following a clear immunization plan can reduce disease risks and boost farm productivity. This guide, written from a veterinary perspective, outlines the types, usage methods, and schedules for common waterfowl vaccines to help farmers and veterinarians. I. Viral Disease Vaccines 1. Duck Plague Vaccine (Duck Viral Enteritis) Vaccine Type: Attenuated live vaccine or inactivated vaccine Target: Ducks, geese Usage: Ducklings and goslings: First vaccination at 7–10 days of age (0. 2–0. 5 mL/bird, subcutaneous or intramuscular injection), second at 30 days (0. 5 mL/bird). Breeders: Booster 1 month before egg production (0. 5–1 mL/bird), repeated every 4–6 months. Precautions: Avoid antibiotics 3–5 days before and after vaccination to prevent immunosuppression. 2. Duck Viral Hepatitis Vaccine (Type I) Vaccine Type: Attenuated live vaccine or inactivated vaccine Target: Ducklings, breeding ducks Usage: Ducklings: Subcutaneous injection at 1–3 days of age (0. 3–0. 5 mL/bird) or gain passive immunity through vaccinated breeders. Breeders: Two vaccinations before egg production (0. 5 mL/bird, 14-day interval) to provide ducklings with passive immunity. Precautions: Vaccinate ducklings early to reduce early infection risk. 3. Avian Influenza Vaccine (H5N1, H7N9) Vaccine Type: Inactivated vaccine Target: Ducks, geese Usage: Ducklings and goslings: First vaccination at 14 days of age (0. 3–0. 5 mL/bird, neck subcutaneous injection), second at 28–30 days (0. 5 mL/bird). Adults: Booster every 4–6 months (0. 5–1 mL/bird). Precautions: Choose vaccines based on local strains and regularly monitor antibody levels.... --- May 16, 2025, China - Wixbio’s CEO, head of the overseas business division, and Middle East sales manager visited Iran in mid-May to visit and evaluate the ICD Group. The visit aimed to strengthen the partnership between the two companies and engage in in-depth discussions and negotiations on future collaboration in animal healthcare. During the visit, the Wixbio delegation held several meetings with ICD Group’s board members, diving into current market trends, technological advancements, and shared interests. With mutual respect and shared goals, both sides discussed their strengths and needs in depth, reaching broad agreement on future partnership directions. After a series of productive negotiations, Wixbio and the ICD Group signed a partnership agreement. The agreement outlines comprehensive collaboration in areas like product supply, technological research and development, and market expansion. This will boost both companies’ global market competitiveness and support the local livestock industry’s growth. Wixbio’s CEO stated: “We’re thrilled to partner strategically with Iran’s ICD Group. Through our joint efforts, we believe we can deliver more high-quality animal healthcare products and services to customers, contributing significantly to the global livestock industry’s healthy growth. ” This partnership marks another major step for Wixbio in the international market, showing the company’s dedication to global partnerships and growth. --- May 28, 2025, Shandong, China — Wixbio has enhanced its services again, using advanced GPS temperature trackers for its latest Turkey order to ensure product quality and timely delivery. This order includes 12,000 bottles of 500ml inactivated trivalent vaccines for Newcastle disease, avian influenza (AI), and duck adenovirus. Given the temperature-sensitive nature of vaccines, keeping a stable cold chain is crucial for their effectiveness and safety. Wixbio uses this cutting-edge technology to keep every step from factory to customer at the right temperature. The GPS temperature trackers allow real-time monitoring of the entire transport process and enable immediate fixes if any issues arise, ensuring top-quality delivery. This batch of custom vaccines was designed to meet the specific needs of the Turkish market, helping local poultry farmers better prevent and control Newcastle disease, avian influenza, and duck adenovirus, which seriously affect poultry health. With Wixbio’s efficient and reliable solutions, Turkish farmers can better safeguard their poultry from these serious diseases. Wixbio’s CEO stated: “We’re dedicated to continually improving our service quality to ensure every customer gets the best products. Introducing GPS temperature trackers is a major step in our service upgrade, showing our dedication to quality and customer satisfaction. ” This service upgrade not only strengthens Wixbio’s partnership with Turkish customers but also highlights Wixbio’s leadership and technical know-how in global animal healthcare. Moving forward, Wixbio will keep exploring new technologies to deliver even better service and support to customers worldwide. --- Antibacterial and anti-mycoplasma drugs are the go-to treatments for preventing and controlling diseases in livestock and poultry. With many types, different mechanisms, uses, and side effects, this guide breaks down their classifications, features, and precautions from a veterinary perspective to help ensure competent and safe use. Classification and How Antibacterial Drugs Work Based on how they work, antibacterial drugs fall into four main types: Bacteria-Killing Drugs (Type I): Like penicillins and cephalosporins, these block bacterial cell wall formation and are great for infections caused by fast-growing bacteria. Static Bacteria-Killing Drugs (Type II): These, such as aminoglycosides and polymyxins, disrupt bacterial cell membranes or protein production, targeting bacteria in a resting phase. Fast-acting bacteria-suppressing Drugs (Type III) include tetracyclines, chloramphenicol, and macrolides. They quickly stop bacterial protein production and can kill bacteria at high doses. Slow-Acting Bacteria-Suppressing Drugs (Type IV): Like sulfonamides, these slow down bacterial metabolism and take longer to work. Effects of Combining Drugs Type I + Type II: Works better together Type I + Type III: May cancel each other out Type II + Type III: Works better together or adds up Type I + Type IV: Works better together Main Types of Antibacterial Drugs and Their Uses Here are the commonly used antibacterial drugs in livestock and poultry farming, with details on how they work, what they treat, and what to watch out for: β-Lactams How They Work: Contain a β-lactam ring that blocks bacterial cell wall formation and triggers enzymes that break down bacteria. Subtypes: Penicillins,... --- Shandong, China, May 14, 2025 -- Wixbio announced the successful shipment of 1,000 500 ml vials of its triple inactivated Infectious Bronchitis (IBH) Types 4, 8, and 11 vaccine to customers in Iraq. This customized product is designed specifically for egg-breeding poultry and aims to help local farmers effectively prevent and control IBH, especially to provide efficient protection against the adenovirus strains prevalent in the region. According to the customer's feedback, the triple inactivated vaccine has performed very well in practice, with a very high protection rate against locally prevalent strains. This has greatly improved the health and breeding efficiency of egg-breeding poultry. This shows that Wixbio's products not only meet the specific needs of the customers but have also been highly evaluated in the market. Infectious bronchitis is an acute, highly contagious infectious disease caused by coronaviruses that poses a serious threat to the poultry industry, especially to egg-laying and breeding birds. By using this specially formulated triple inactivated vaccine, farmers can effectively reduce the incidence of the disease, improve egg production, and minimize economic losses. To ensure the vaccine's activity and efficacy during transportation, all products are packaged and shipped according to strict cold chain management standards. This ensures that the vaccines arrive at their destination in the best possible condition, providing customers with a reliable guarantee. This shipment further strengthens Wixbio's relationship with its Iraqi customers and demonstrates the company's expertise and market leadership in the global animal healthcare sector. Wixbio continues to develop high-quality animal healthcare... --- Shandong, China, May 14, 2025 -- Wixbio today announced the successful shipment of another large-scale order for the Turkish market, totaling 10,500 500 500 ml vials of the triple custom inactivated vaccine against Newcastle Disease (ND), Avian Influenza (AI H9 subtype), and Duck Adenovirus (FADV). This shipment not only reflects the high level of customer trust in Wixbio's products but also signifies the product's continued success in the Turkish market and favorable market feedback. The vaccines are tailored to the specific needs of the Turkish customer. They are designed to help the local farming industry effectively prevent and control these diseases that seriously affect poultry health. Newcastle disease, avian influenza subtype H9, and duck adenovirus cause serious health problems in poultry, reducing productivity and resulting in significant economic losses. This triple vaccine is therefore essential for safeguarding poultry health and improving farm efficiency. Given the customer's multiple repurchases and the positive feedback from the market, this shows that the quality and effectiveness of Wixbio's products are well recognized. To ensure the vaccine's activity and efficacy during transportation, all products are packaged according to strict cold chain management standards to ensure they reach their destination at the highest quality. This shipment further strengthens Wixbio's relationship with its Turkish customer and demonstrates its global animal health leadership. By providing efficient and safe solutions, Wixbio supports the growth of the Turkish farming industry and sets an example for its partners in other regions. Wixbio is a company specializing in the development, production, and... --- May 14, 2025, Shandong, China -- Wixbio has successfully completed a major order for 6,000 500ml vials of inactivated avian influenza (H5+H9) vaccine from its Shandong production base to a customer in Vietnam. The vaccines have been shipped to Vietnam as scheduled and will be delivered soon. This shipment is based on Vietnamese customers' high recognition of Wixbio products. After using the same vaccine in the previous stage, the customer conducted strict laboratory tests. The results showed that the antibody level in the poultry increased significantly after vaccination, and the vaccine protection rate was excellent, effectively controlling the risk of avian influenza spreading in the local farms. As a result, the vaccine has quickly won the trust and praise of farmers and veterinary organizations in the Vietnamese market. Avian influenza subtypes H5 and H9 are primary disease threats to the global poultry farming industry, characterized by rapid transmission, high pathogenicity, and economic losses. The avian influenza (H5+H9) inactivated vaccine developed and produced by Wixbio adopts an advanced process proportioning, with stable immunogenicity and high safety, which is suitable for efficient prevention and control in large-scale farming environments. To ensure the quality and activity of the vaccine during transportation, this batch of products all adopts professional cold chain transportation solutions, with temperature control throughout the whole process. This ensures that the vaccine is effective when it arrives at the destination. Wixbio said it will continue to deepen its commitment to the international market, adhere to the customer's needs as the core,... --- Wednesday, May 7, 2025 -- A customer from Iraq recently arrived at Wixbio's manufacturing facility in China for a fruitful visit and exchange. The purpose of the visit was to gain insights and training on products already registered and sold in the Iraqi market, including the inactivated avian influenza (H5+H9) vaccine, the ND-AI-IBH vaccine, the adenovirus vaccine, and the ND & AI Reassortant Virus Vaccine, among others. During the several-day visit, the Iraqi customer and Wixbio's technical team discussed key topics such as strain matching, testing methods, and immunization procedures. The two sides exchanged ideas and shared their experiences and technical insights to improve the local application of these products and better serve the needs of the Iraqi market. Specifically, the discussions focused on the following areas: Strain Matching: Based on the characteristics of the pathogens in the region, discussions were held on selecting the most suitable vaccine strains to ensure optimal vaccine protection. Testing methods: Introduction and training on the latest laboratory testing techniques for more accurate vaccine efficacy and disease surveillance assessment. Immunization procedures: To achieve the best preventive effect, optimal immunization schedules for different types of poultry and local breeding environments must be developed. This face-to-face interaction strengthened the relationship between the two parties and laid the foundation for further expansion of the cooperation area. Wixbio said it will continue to be committed to providing high-quality animal healthcare solutions to its global customers and hopes that such interactions will help more farmers prevent and control diseases effectively... --- Shandong, China, May 7, 2025 -- Wixbio today announced the successful shipment of its customized Duck Adenovirus Inactivated Vaccine from its manufacturing site for customers in Vietnam. The shipment includes 500 vaccine vials designed to help Vietnamese farmers effectively prevent and control duck adenovirus infections and protect poultry health. Duck adenovirus is a highly infectious and pathogenic pathogen for duck flocks. It can cause a wide range of serious diseases, including pericardial effusion and hepatitis, resulting in significant economic losses for the duck industry. In response to this threat, Wixbio has developed and produced a high-quality inactivated adenovirus vaccine to meet the needs of the Vietnamese market. To ensure the activity and potency of the vaccines during transportation, all products are packed and shipped according to strict cold chain management standards. This not only ensures the vaccines' safety but also reflects Wixbio's strict requirements on product quality control. The shipment of Duck Adenovirus Inactivated Vaccine to Vietnam marks Wixbio's further expansion of its international presence and strengthens its relationship with its Southeast Asian partners. By providing efficient and safe animal healthcare solutions, Wixbio is committed to helping farmers worldwide cope with various disease challenges and promote the healthy development of the livestock industry. --- Beijing, April 30, 2025 — A significant shipment of animal vaccines has been airlifted from Beijing to Baghdad, Iraq, to support Iraqi clients in preventing and controlling poultry diseases. The consignment includes 4,000 vials of Newcastle Disease (ND, G7 strain) and Avian Influenza (AI, H9 subtype) dual inactivated vaccine, 5,000 vials of Newcastle Disease (ND) live vaccine, and 5,000 vials of Newcastle Disease (ND) and Infectious Bronchitis (IB) dual live vaccine. This delivery of high-quality vaccines marks a vital contribution to the Middle East's poultry industry, particularly in combating serious threats like Newcastle Disease and Avian Influenza. These vaccines will help prevent and control disease outbreaks, safeguard poultry health, and ensure the safety and stability of the food supply. To maintain the vaccines' potency and efficacy during transportation, all vials were packaged under strict cold-chain management standards and shipped via the fastest air transport route to their destination. This ensures the vaccines' safety and effectiveness and underscores the sender's commitment to rigorous quality control. With the successful dispatch of this vaccine batch, they are expected to arrive in Iraq soon and be promptly distributed to areas in need, addressing potential disease risks. This initiative strengthens agricultural and livestock cooperation between China and Iraq and robustly supports Iraq's local poultry industry. WIXBIO is dedicated to delivering efficient and safe animal health solutions, helping farmers worldwide overcome various challenges, and promoting the healthy development of the livestock industry. Through continuous technological innovation and service optimization, WIXBIO has become a trusted partner for... --- Shandong, China, April 29, 2025 -- Wixbio announced the successful shipment of customized samples of inactivated duck eutheria (Reo) vaccine for the Vietnam market. The shipment includes 500 vials of the vaccine in 250ml size, which will be used for evaluation and testing purposes to meet the specific needs of customers in Vietnam. Duck eutheria virus (Reo) is a pathogen that has a profound impact on the duck industry, causing growth retardation, reduced feed conversion, and high mortality. Therefore, an effective vaccine against this virus is essential to improve the efficiency and profitability of duck farming. Wixbio developed and produced this high-quality inactivated vaccine sample according to the specific requirements of Vietnamese customers. To ensure the vaccine's activity and potency during transportation, all samples were packed and shipped according to strict cold chain management standards. This not only ensures the vaccines' safety but also demonstrates Wixbio's stringent requirements for product quality control. The shipment of inactivated duck eutheria (Reo) vaccine samples to Vietnam marks Wixbio's further expansion of its international footprint and strengthens its relationship with Southeast Asian partners. Wixbio is committed to helping farmers worldwide meet disease challenges and promote healthy animal husbandry by providing adequate and safe animal health solutions. About Wixbio: Wixbio is a company specializing in the research, development, production, and marketing of veterinary drugs and animal vaccines. With advanced technology and high-quality products, the company provides strong support to the livestock industry worldwide. Wixbio always adheres to the customer's needs as a guide and constantly... --- As intensive farming models grow, the backdrop of antibiotic restrictions and reduced reliance on antibiotics has made poultry diseases increasingly complex. Take 2024, for example—new outbreaks of old diseases stood out sharply. Immunosuppressive diseases like infectious bursal disease, swollen head syndrome, and viral arthritis have hit farmers hard, with reduced egg production in flocks often popping up in specific regions. Of course, several diseases can cause egg production to drop, including Newcastle disease, avian influenza, infectious bronchitis, and rhinitis. Industry observations and data show egg drop syndrome has a higher detection rate in areas with dense layer and breeder chicken farms, clearly creating challenges for existing immunization programs. What is Egg Drop Syndrome? Egg Drop Syndrome (EDS’76) is a disease caused by an adenovirus, mainly hitting laying hens—especially those at peak production—causing a sharp drop in egg output and poor eggshell quality. While outbreaks mainly affect laying hens, ducks and geese are typically considered the natural hosts of EDSV. The virus has a long latent period and can spread vertically and horizontally. Horizontal transmission is slow and intermittent, taking about 11 weeks to spread through an entire cage. Clinical Symptoms of Egg Drop Syndrome Drop in Egg Production: Egg production falls suddenly and rapidly, lasting 4-10 weeks, with output potentially dropping by 40%-50%. Production may recover later, but the total loss is typically 10-16 eggs per hen. Abnormal Eggs: Thin-shelled, soft-shelled, and shell-less eggs are common. Thin-shelled eggs are often rough or have a granular texture at one end; egg... --- The bursa of Fabricius, also known as the cloacal bursa, is a unique central immune organ in poultry, playing a key role in developing the avian immune system. Lately, atypical bursal disease cases have been on the rise. When it hits, it means the vaccine didn’t work, or there’s a wild virus infection. Layer pullet farms see the highest infection rate at 47. 53%, followed by white-feather broilers, 817 broilers, and yellow-feather broilers. The disease mostly strikes birds aged 30-45 days, though some cases are as early as 18 days. Multiple IBDV strains are circulating in China, with nVarIBDV and vIBDV being the two main ones that are hurting the poultry industry. Transmission of Bursal Disease and Advantages of Live Vaccines IBDV in Chicken Farms The bursal disease (IBDV) is tough to wipe out and can spread from one flock to another. New chicks in the same house could face an outbreak if a previous flock had variant or highly virulent IBDV strains. New variant strains also cause big problems like intestinal issues (e. g. , gizzard erosion) and slow weight gain. Maternal Antibodies High maternal antibodies protect chicks from early IBDV infection. But as chicks get older, these antibodies fade and eventually disappear, making the flock more susceptible. During this time, reducing stress is critical to avoid triggering bursal damage. Advantages of Live Vaccines Live vaccines boost immunity to fight IBDV infection, quickly setting up protection to block wild virus infection. However, the “colonization” of IBD live vaccines hinges... --- April 28, 2025, Shandong, China—WixBio has shipped a refrigerated container of AI vaccines, Newcastle Disease triple vaccine, and veterinary drugs from Shandong to Vietnam. This shipment will provide Vietnam's poultry farmers with a "vaccination kit" against highly pathogenic avian influenza (HPAI) and other epidemics and help the local poultry industry cope with the high incidence of avian infectious diseases during the rainy season. Vaccines sent to Vietnam Avian Influenza (H5+H9) Bivalent Vaccine Function: Prevent H5N6 and H9N2 avian influenza viruses, responsible for Vietnam's highest poultry mortality rate. Advantages: The vaccine is effective for 18 months (the regular vaccine is only 12 months), potent antibodies can be produced 21 days after injection, and protection lasts 1 year. It is especially suitable for Vietnam's high-temperature and high-humidity storage environment in the rainy season. ND-IB-AI Vaccine for Chicken Effect: Preventing three epidemics in one injection, reducing the stress reaction of poultry. Advantage: It is effective 7 days after injection, and the antibody rate is more than 94%, making it especially suitable for rapid immunization in small and medium-sized farms in Vietnam. Supporting products: The simultaneous export of disinfectants, immune enhancers, and virus detection kits will help farmers realize the management process of "disinfection—epidemic prevention—monitoring. " Cold chain transportation to ensure vaccine activity To cope with the hot and humid climate in Vietnam, WixBio adopts the following measures to ensure vaccine quality: Real-time temperature control: GPS temperature and humidity monitoring is installed in the containers to maintain 2-8℃ throughout the process, with automatic alarms... --- Overview of Tembusu Virus Tembusu disease is an infectious illness caused by the Tembusu virus, part of the Ntaya virus group in the Flavivirus genus. It causes laying ducks' egg production to plummet (from 90% to 10% or even stop altogether), reduces appetite in ducklings, and slows their growth. Originally called "duck hemorrhagic oophoritis" or "duck viral encephalitis," the virus was first found in meat ducks in 2011. By 2012, it was confirmed as the duck Tembusu virus. So far, it can infect waterfowl, commercial laying hens, and breeder chickens. Pathogenic Characteristics of Tembusu Virus Classification Standards Tembusu disease belongs to the Flaviviridae family, Flavivirus genus, Ntaya virus group. Morphological Features The virus particles are spherical, 45–50 nm in size, and mature particles are wrapped in a phospholipid bilayer featuring glycoprotein spikes and an icosahedral nucleocapsid. Genomic Structure The DTMUV genome is a single-stranded positive-sense RNA virus, about 11 kb long with 10,990 nucleotides. It encodes three structural proteins: capsid protein (C), prM protein (precursor to M protein), and envelope protein (E); and seven non-structural proteins: NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5. The C protein has low amino acid similarity, contains many basic amino acids, and helps in virus assembly. The prM gene produces the prM protein, which matures into the M (membrane protein). The M protein binds tightly with C and E proteins and aids in virus packaging. Pathogenic Features The virus particles are spherical, 45–50 nm in size, with mature particles enclosed in a phospholipid bilayer... --- China's poultry farming accounts for 50% of the world's poultry population, with about 17 billion birds slaughtered annually. In the livestock and poultry farming industry, the prevention and control of epidemics is always a top priority. Avian influenza and Newcastle disease are the "top killers" in the global poultry farming industry. Newcastle disease, as a serious threat to the health of poultry, has long brought substantial economic losses to farmers. The successful research and development of the Newcastle Disease Gene VII vaccine has forged a solid defense for the prevention and control of poultry disease and has become the dawn of the healthy development of the poultry farming industry. With the continuous evolution of the Newcastle disease virus, the genotype VII strain has become the primary epidemic strain in recent years. It spreads fast and is highly pathogenic, and the control effect of traditional vaccines is not good. Once the poultry is infected with Newcastle disease, there will be dyspnea, diarrhea, neurological disorders, laying hens egg production decreasing significantly, young poultry mortality being very high, and so on, seriously affecting breeding efficiency. The Newcastle disease Genotype VII marker vaccine has been developed in response to this critical situation. The vaccine has excellent immunity against genotype VII Newcastle disease virus. WIXBIO is collaborating with China's most senior poultry research institute to launch the Newcastle disease Gene-VII marker inactivated vaccine. The vaccine has been licensed for sale in China and has received excellent customer feedback. The technologies adopted in developing this vaccine:... --- Vaccines have always been one of the most potent weapons in humanity's long battle against disease. With the rapid development of science and technology, a new type of vaccine, the subunit vaccine, is gradually emerging, bringing new hope for preventing and controlling human and animal diseases. Conventional vaccines contain the complete or partial structure of the pathogen. Although they are effective in stimulating an immune response, they may also bring about some adverse reactions due to the presence of other components of the pathogen. Subunit vaccines, conversely, are unique in that they select only key parts of the pathogen that are immunogenic, such as specific proteins or polysaccharides, as antigenic components. This precise design makes subunit vaccines extremely safe. By removing the parts of the pathogen that can cause adverse reactions, the vaccinated animal receives immune protection while the risk of side effects is significantly reduced. Subunit vaccines are no less effective than traditional vaccines in terms of immunization effectiveness. The carefully selected antigenic components precisely stimulate the body's immune system to produce a highly targeted immune response. Numerous clinical trials have shown that subunit vaccines can induce the body to produce high levels of specific antibodies, forming a strong defense barrier against the target pathogen. Moreover, the immune response is long-lasting, providing effective protection for a long period and reducing the need for frequent vaccinations. Leading international animal health companies have launched a series of animal subunit vaccines. For example, the boehringer-ingelheim PCV 2 type subunit vaccine, MSD APP... --- Infectious bursal disease (IBD), first called “Gumboro Disease” (named after the first occurrence of the disease in the Gumboro region of the United States) is a highly contagious, fatal and immunosuppressive disease. It mainly affects chickens (especially chicks and young chickens), causing significant economic losses to the global poultry industry. This article will introduce in detail the use methods and precautions of the Gumboro disease vaccine to help farmers effectively deal with this disease. Etiology of Gumboro disease The virus belongs to the genus Avibirnavirus of the Birnaviridae family. It is a double-stranded RNA virus that mainly infects the bursa of chickens (which is a key immune organ) and causes immunosuppression. Studies have shown that there are two serotypes of IBDV, but only serotype 1 is pathogenic to chickens, mainly infecting young chickens 3-6 weeks old. How Gumboro disease spreads? The Gamboro virus has no envelope and is highly resistant to drugs. It can survive in contaminated feed, water, feces, and insects (such as Alphitobius) for more than 50 days, and even after the infected chickens are removed, it can survive in the chicken coop environment for more than 4 months. Transmission is mainly through direct contact or contaminated feed, water and feces infection, and infected chickens discharge high levels of virus within about 2 weeks after infection. Infectious Bursa Clinical Symptoms Common symptoms Depression: The chicken appears listless and has reduced activity. Loss of appetite: Chickens reduce or stop eating. Gather together: The chickens tend to huddle together with... --- Infectious Bronchitis (IB) in poultry is an acute and highly contagious respiratory disease caused by the Infectious Bronchitis Virus (IBV), which widely affects chickens, especially laying hens and broilers. The disease not only causes respiratory symptoms, but may also cause decreased egg-laying performance and kidney damage, causing significant economic losses to the poultry farming industry. This article will introduce in detail the etiology, symptoms, diagnosis, and scientific prevention and treatment options of infectious bronchitis in poultry to help farmers effectively deal with this disease. Etiology of infectious bronchitis Pathogen: IBV belongs to the family of Coronaviruses (Coronaviridae) and is a single-strand positive-strand RNA virus. The virus has a variety of serotypes (such as M41, Conn, Ark, etc. ) and genotypes, which increase the difficulty of prevention and control because of its variability. Susceptible groups: Chickens of all ages can be infected, but chicks and laying hens are particularly affected. Infectious bronchitis (IB) is a highly contagious viral disease that affects chickens of all ages and types. The pathogenic organism is a single-stranded RNA virus of the coronavirus family, which mainly affects chickens. It affects the upper respiratory tract, the reproductive tract of female chickens, and some strains cause nephritis. Different serotypes and genetic types of viruses have been identified all over the world, and in most cases there is no cross-protection. The virus is present in commercial chickens and backyard chickens. Recently, IBV and IBV-like strains have been found in poultry other than chickens, such as geese, ducks and pigeons,... --- Identification diagnosis and prevention and control of infectious coryza Infectious coryza is an acute or subacute respiratory disease of chickens caused by Avibacterium paragallinarum. It is characterized by inflammation of the nasal cavity and sinuses, sneezing, nasal discharge, and facial swelling. This disease occurs in breeding chickens and laying hens, causing slow growth and development and poor evenness in breeding chickens, and increased culling rate and significant drop in egg production in laying hens(10%-30%). Pathogen Avibacterium paragallinarum is a Gram-negative pathogen. There are three serovars of A. paragallinarum(A, B, and C). These are not cross-protective so it is essential that any vaccines contain the appropriate serovar for that population of birds. Epidemiology Susceptible animals Chickens over 4 weeks of age of all breeds are susceptible, and chicks under 1 week of age have a certain resistance. Other infected poultry(such as turkey, duck, goose, and pigeon) and study animals (such as rabbit, mouse, guinea pig), whether naturally or artificially, have strong resistance to the disease. Route of transmission and source of infection The disease is mainly transmitted by the excretion from the respiratory tract and digestive tract of infected chickens. Sick chickens, especially those with chronic diseases, are the main source of infection. The shed pathogens spread through the air, dust, drinking water, feed and so on. Characteristics This disease is not obviously seasonal, but due to poor ventilation, its incidence is relative high in cold season. Clinical symptoms Affected chickens initially have no obvious symptoms, only present with sneezing and... --- Newcastle disease is an highly contagious viral disease caused by paramyxovirus. It mainly manifests as dyspnea, diarrhea, disordered nervous system, bleeding mucous membrane and serous membrane in sick chicken.  And once chicken are affected, the mortality will be as high as 90%.  With a high mortality rate and the severe economic consequences of its outbreaks in commercial poultry, the disease is reportable to the World Organization for Animal Health. Therefore, it is essential for chicken farmers to do a good job in the prevention and treatment of Newcastle disease, because a small error in it will lead to heavy losses. Next, let us to learn about the Newcastle disease. Symptoms of Newcastle disease in poultry Sudden death and high mortality Sharp decreased egg production. Eggs may be abnormal in color, shape, or surface, and have watery albumen. Difficult breathing, sneezing, coughing, gasping Twisting of neck, circling, trembling, stiffness, spasms, depression, nervous manifestations Drooping wings, ruffled feathers Reduced feed consumption Decreased activity Swelling around the eyes and neck Watery diarrhea If you find any of the above signs in your chicken flock, maybe the virulent Newcastle disease is attacking your chickens. You could check postmortem lesions as follows for primary diagnosis: Larynx edema or pointy petechiae; Adenogastric papillomedema, bleeding or ulceration; Swelling or slight bleeding of the descending duodenum, 2-3cm at the front and back of the yolk stalk and lleum lymphatic follicles; Brush rectal bleeding. Of course, the diagnosis must be confirmed by virus isolation, virus detection by RT-PCR or immunohistochemical staining assays,... --- Infectious coryza is a common respiratory disease caused by Haemophilus paragallinarum that invade the respiratory tract of chickens. It is common in poultry farming, especially in intensive farming environments. Infectious coryza is usually difficult to distinguish from other respiratory diseases. The disease is mainly characterized by inflammation of the nasal cavity, runny nose, swelling around the eyes and dyspnea. If left untreated, it may lead to a decrease in the production performance of the flock, such as a decrease in egg production rate or a slowdown in growth rate. The following will introduce in detail the symptoms, diagnosis and treatment methods of chicken infectious coryza to help farmers effectively deal with this disease. What is Chicken infectious coryza? It is an acute respiratory tract disease caused by the bacteria Haemophilus paragallinarum or Avibacterium paragallinarian. These bacteria are most common in warm environments. Infectious coryza can also be called haemophilus infection. It is a respiratory disease that causes chickens to exhibit respiratory distress and spread through respiratory droplets. Respiratory droplets from coughing or sneezing by infected birds can be inhaled by other birds and then spread the infection. The spread of Chicken infectious coryza In most cases, infectious coryza is not fatal. Survivors of infection will build immunity to bacteria, but they will still be carriers of the disease for the rest of their lives. Non-infected chickens exposed to infected chickens are also considered carriers of the disease, even if they never show any symptoms. This is because chickens can build... --- Poultry vaccination is a crucial measure for ensuring the health of poultry and improving farming efficiency. Vaccines can effectively prevent infectious diseases, reduce disease transmission, and safeguard poultry production capacity and food safety. In this article, we will introduce the common types of vaccination for poultry to help you better understand the role and use of vaccines. Live Vaccines and Inactivated Vaccines In poultry vaccination, the two most common types of vaccines are live vaccines and inactivated vaccines. Live Vaccines These are made from attenuated pathogens or viruses. The pathogens in live vaccines still retain some infectivity, but they have been specially treated to weaken their virulence. This allows them to stimulate the poultry immune system to produce an immune response without causing disease. Live vaccines typically induce a stronger immune response and provide longer-lasting immunity. Examples include vaccines for avian influenza and Newcastle disease. Inactivated Vaccines These vaccines are produced by killing the pathogens through physical or chemical methods, rendering them non-infectious, yet still capable of retaining their antigenic properties. Inactivated vaccines are generally safer and more suitable for mass vaccination. Common examples include vaccines for avian cholera and avian leukemia. Monovalent Vaccines and Combined Vaccines Poultry vaccines can also be classified into monovalent and combined vaccines based on their composition. Monovalent Vaccines These vaccines are designed to target a single pathogen, such as a specific virus or bacterium. When administering monovalent vaccines, multiple doses are often required based on the type of pathogen. Examples include vaccines for avian... --- What is rabies？ Rabies virus is a highly dangerous infection that has serious effects on the brain. It is spread through contact with the saliva of infected animals and poses a risk to pets, livestock, wild animals and humans. Most cases of rabies infection involve wild animals. Bats, raccoons, foxes and skunks are the main carriers of the virus. Sadly, rabies is almost always fatal once symptoms are manifested. The incubation period of rabies The incubation period is the time between exposure to the rabies virus and the onset of symptoms of the disease. In most cases, your pet will begin to show signs of disease within 2 weeks of exposure, but sometimes symptoms may take several months to appear. This is why it is important to get your dog vaccinated. If your pet is infected with rabies, it can spread the virus to other pets and humans until 10 days before it begins to show any signs of disease. How dogs get rabies？ The virus can spread from infected mammals to any other mammals, including wild animals, pets, livestock, and humans, through saliva. If your pet is bitten by a rabid animal, or its eyes, nose, mouth, or open wounds are infected with the saliva or brain/spine tissue of the infected animal, whether dead or alive, it will be infected with rabies. Symptoms of rabies in dogs Different barking Excessive drooling Uncharacteristically aggressive, fearful Overreaction to touch, sound, or light Bite or lick the exposed wound area Difficulty swallowing... --- Coccidiosis is caused by protozoan parasites of the genus Eimeria. These parasites are host-specific, and many species occupy specific sections of the intestine. Coccidiosis is probably one of the most common diseases affecting small groups around the world, leading to loss of performance and even mortality. Vaccination, preventive medication and good management practices can help control the disease. What is chicken coccidiosis? Coccidiosis is a common and sometimes fatal intestinal disease caused by parasites that attach to the intestinal wall of chickens. This parasitic invasion can damage the intestine and prevent the host chicken from absorbing nutrients that are essential for its survival. Coccidiosis begins with oocysts, or tiny eggs, passing through chicken feces. The oocysts can hibernate in the soil for up to a year and will not be infectious (spores) until the surrounding conditions support their survival. Young chickens (under six months old) are at greater risk of infection because they have not had time to develop their natural immunity, but adult chickens will also be affected. Symptoms of coccidiosis Coccidiosis develops rapidly, with an incubation period of 4 to 8 days. Symptoms may develop gradually or appear suddenly. It is not uncommon for chickens to look good one day and become seriously ill the next day, or even die. The most common symptom of the disease is blood or mucus in chicken feces. However, red chicken manure is not always an indicator of coccidiosis. Chicken manure may also appear brown-red due to the normal shedding of cecal... --- Recently, WixBio ND-AI-IBH Vaccine (Newcastle Disease, Influenza, and Adenovirus Triple Vaccine), an inactivated poultry vaccine, was successfully shipped to the Middle East. This cooperation marks another important milestone for Wixbio in the international veterinary market and provides a powerful disease-prevention solution for the local poultry farming industry. Product Advantages and Features Based on advanced cell suspension culture and prokaryotic expression technologies, the new vaccine is characterized by its high antigenic content, long immunity period, and broad applicability. Integrating the prevention of three major poultry diseases in a single dose not only simplifies the immunization procedure but also effectively reduces the stress caused by multiple chicken vaccinations. In addition, the scientifically designed immunization program ensures adequate protection for chickens of different age groups, which helps to improve the farm's overall production performance. A new chapter of international cooperation With the successful delivery of this batch of vaccines, Wixbio will further strengthen its partnership with its Middle East distributors in a joint effort to improve animal healthcare in the region. In response to the unique needs of the Middle East market, the company will continue to provide technical support and service guarantees to ensure the best use of vaccines in the region. At the same time, this also reflects Wixbio's firm commitment to actively expanding overseas markets and serving global customers. Wide Market Prospects The widespread spread of H9 subtype avian influenza and Group I 4 avian adenovirus among poultry has caused significant economic losses to the poultry industry in recent years.... --- It is the owner's responsibility to vaccinate pet dogs regularly every year, and regular dental cleaning is also an important part of maintaining the dog's oral health. Many pet owners may have a question: Can the dog's annual vaccination be done during dental cleaning? Today, let's explore this issue. Vaccination and dental cleaning: two different medical needs First of all, we must make it clear that vaccination and dental cleaning are two completely different medical procedures. Vaccination is to enhance the dog's immunity and prevent infectious diseases. Dental cleaning is to remove plaque and tartar on the teeth, maintain oral hygiene, and prevent periodontal disease. Dental cleaning usually requires anesthesia, while vaccination usually does not require anesthesia. This means that although these two procedures can be performed on the same day, their operation methods and purposes are different, and decisions need to be made based on the dog's health status. When can you consider doing it at the same time? If your dog is in good health, the veterinarian believes that it can withstand anesthesia, and has no other health problems, then you can consider doing vaccination and dental cleaning at the same time under the same anesthesia. This not only saves the dog's anesthesia times, but also reduces the burden on the owner and pet. However, it is worth noting that anesthesia for dental cleaning can affect the dog's physical condition. For older dogs or dogs with heart or respiratory diseases, the veterinarian may recommend separate procedures to avoid... --- Have you ever had to temporarily leave your dog and entrust it to a pet boarding center? Whether it is a short-term trip or an emergency job transfer, ensuring the health and safety of the dog during the boarding period is the top priority of every pet owner. When taking a dog to boarding, many boarding centers require the dog to be vaccinated with certain vaccines. These vaccines are to ensure the health and safety of the dog during the boarding period, and also to prevent the spread of some infectious diseases between dogs. So, what vaccines do dogs need to be vaccinated before boarding? Let's take a look at them one by one. Vaccinations Needed for Dog Sampling Rabies vaccine Rabies is a deadly viral disease that can infect almost any animal. For the protection of dogs as well as humans, the vast majority of places require dogs to be vaccinated against rabies, which is one of the most basic requirements when boarding a dog. In many places, rabies vaccination is not only necessary for boarding, it is mandatory by law. You can choose our Rabies Vaccine on our website. Canine Distemper Vaccine Canine distemper is a viral disease that can attack a dog's respiratory, digestive, and nervous systems, and can cause death in severe cases. This vaccine is usually given as part of a combination vaccine, which means it is given with several other vaccines to prevent diseases like canine distemper effectively. Canine Parvovirus Vaccine Canine parvovirus is... --- What is the Newcastle disease virus? Newcastle disease virus (NDV), also known as Avian paramyxovirus 1 (APMV-1), is a virus belonging to the Paramyxovirus family (Paramyxoviridae) Paramyxovirus genus (Paramyxovirus). It can cause a highly contact, acute, and severe infectious disease called Newcastle disease (ND). This disease mainly affects poultry, especially chickens, but it can also infect other birds, such as beaded chickens, turkeys, pheasants, peacocks, etc. Ducks and geese have a certain resistance to this disease, while mammals usually have a strong resistance to the disease. Structure of Newcastle disease virus The genome of NDV is single-stranded negative RNA, and mature virus particles are spherical in shape, with a diameter of about 120-300 nm. The surface of the virus has radially arranged fibrous processes, and these structures are essential for it to infect host cells. Symptoms of Newcastle disease in chickens Newcastle disease exhibits a variety of clinical symptoms, including respiratory, nervous, and digestive system symptoms. Respiratory symptoms Dyspnea is manifested as coughing, sneezing, and breathing with mouth open. Breathing is often accompanied by “grunting” or other abnormal sounds. Digestive system symptoms Discharge yellow-green thin stools, which may be accompanied by blood. Appetite is reduced, and drinking water is increased. Nervous system symptoms Mental malaise, neck twisting, unsteady standing, muscle tremor,r, and other manifestations. Some chickens may experience paralysis or paralysis. The incubation period of the disease is usually 2 to 15 days, and it can spread rapidly after the onset of the disease, and the mortality rate can be... --- In December 2024, Mr. SAFAROV, CEO of PHARMINDUSTRIA from Russia, and Mr. SIDAROVICH from Belarus were invited to visit our company WIXBIO, the purpose of the visit is to strengthen the communication and cooperation between the two sides in the animal vaccine industry, and to jointly promote the advancement and development of the technology of disease prevention and control. Visiting the factory and R&D centre Mr.  SAFAROV and Mr. SIDAROVICH firstly visited the vaccine production plant and R&D organisation. From the laboratory to the processing workshop, and then to the quality inspection centre and packaging line, the customer highly appreciated the modern production and quality control system of our vaccines. Afterwards, the delegation visited our R&D organisation and highly praised our R&D capability, technology level and research team. The following is the photo of the customer visiting the production workshop: In-depth meeting discussion After the visit, Mr.  SAFAROV and Mr. SIDAROVICH had a 6-hour meeting with WIXBIO experts. Both sides had an in-depth discussion on the current epidemic trend, product development and innovation, technology transfer and key technology development. During the discussion, both sides were immersed in a strong academic atmosphere and had an in-depth discussion on the animal disease epidemiological situation in Russia and neighbouring countries, cutting-edge technology, market demand for animal vaccines and other issues. Especially for the technical problems of avian Newcastle Disease, Fasciola, Infectious Bronchitis and other vaccines, Mr.  SAFAROV put forward his own unique insights, and our expert team also answered them one by one. Laying the foundation for cooperation The... --- Avian influenza, also known as bird flu, is an acute infectious disease caused by avian influenza viruses (H5N1, H7N9, etc. ), which mainly infects birds, including poultry (such as chickens, ducks, geese, etc. ) and wild birds. The avian influenza virus not only poses a huge threat to poultry but can also cause the death of a large number of poultry in severe cases. It may also spread across species to humans and even cause a large-scale public health crisis. Therefore, understanding the transmission routes of avian influenza and taking effective preventive measures, especially animal vaccination, are the key to controlling the epidemic. This article will explore how avian influenza is transmitted and how to prevent the spread of the disease, and help farmers and the public understand the role of vaccines and vaccination recommendations. How is bird flu spread? Spreading of the Flu The transmission of avian influenza virus is very complex and mainly spreads through the following ways: Direct contact transmission Avian influenza virus mainly exists in the body fluids of infected birds (such as saliva, feces, and eye and nasal secretions). If healthy birds come into contact with these virus-carrying objects or secretions of infected birds, they are easily infected. For example, pecking at each other and touching feces between birds may become transmission routes. Airborne transmission When sick birds cough or sneeze, the virus may spread into the air in the form of droplets. If other birds inhale the air containing the virus, they will be... --- Infectious Bursal Disease (IBD) causes farmers great headaches in chicken farms. It not only affects the healthy growth of chicks but can also lead to large-scale mortality in severe cases, causing significant economic losses in the poultry industry. So, what exactly is IBD, and how can we effectively prevent, control, and treat it? Let's dive into the details. What is Infectious Bursal Disease? Infectious Bursal Disease (IBD), also known as Gumboro Disease or Infectious Bursa Inflammation, is an acute, highly contagious, and immunosuppressive avian infectious disease caused by a virus of the genus avian birnavirus of the family Birnaviridae. It mainly affects chicks between 3 to 6 weeks of age. Although adult chickens can also be infected, the symptoms tend to be milder. The Bursa of Fabricius is a vital immune organ in chickens, responsible for producing B lymphocytes to help fight foreign pathogens. It is this key area that IBDV attacks, causing the chicken's immune system to be severely suppressed, thus making it more susceptible to other pathogens. Sick chickens usually show symptoms such as fever, loss of appetite, diarrhea, and loose feathers, which may lead to death in severe cases. Especially in an environment with imperfect vaccination or improper management, bursal disease can spread rapidly and cause large-scale epidemics. How is Infectious Bursal Disease Transmitted? IBD spreads through a variety of routes. The virus is primarily transmitted via feces, air, and contaminated equipment. The excrement of infected chickens contains a large amount of virus, and the surrounding chickens... --- Infectious Coryza is like a chicken getting a serious cold. It is a common respiratory disease caused by bacteria that invade chickens' respiratory tracts. Infectious coryza is usually difficult to distinguish from diseases such as avian influenza, Newcastle disease, infectious laryngotracheitis, and infectious bronchitis, but understanding the specific symptoms of infectious coryza can help you identify this infection in your flock. In addition to understanding the symptoms of infectious coryza, the prevention and treatment of this disease are also essential for the healthy growth of the flock and the stability of egg production. What is infectious coryza in chickens? Infectious coryza is an acute respiratory disease of chickens caused by Paragallinarum Avibacterium, a bacterium that apparently affects only chickens. Reports from quail and pheasants may describe a similar disease caused by a different bacterium. Clinical signs include decreased activity, nasal discharge, sneezing and facial swelling. Occurs primarily in pullets and laying hens and occasionally in broilers. Usually occurs in adult chickens; susceptibility increases with age; however, the disease has also been reported in very young chicks (e. g. , 2 weeks of age). Can chicken infectious coryza be transmitted to humans? Chicken infectious coryza is a disease caused by the bacterium Paragallinarum Avibacterium that usually only infects chickens, especially laying hens. Chicken infectious coryza is not a zoonotic disease, so it is not usually contagious to humans. The cause of chicken infectious coryza? Chicken infectious coryza is an acute respiratory infectious disease caused by chicken infection with Paragallinarum Avibacterium. Most... --- From December 11~13, 2024, Wixbio participated in the 2024 high-level foreign expert Qiluxing and International Animal Medicine Industry Technology Seminar held at Binzhou Institute of Animal Husbandry and Veterinary Medicine in Shandong Province. The event was hosted by Binzhou Science and Technology Bureau and Binzhou Agriculture and Rural Affairs Bureau. Experts, scholars and researchers from Shandong Binzhou Institute of Animal Husbandry and Veterinary Medicine, Wixbio, Russia's PHARMACINDUSTRIA company and many other units were invited to participate in the meeting. The conference focused on the cutting-edge technology of the international animal medicine industry and adhered to the “four aspects”. The participants conducted in-depth discussions on the current challenges facing the field of animal medicine and their solutions. At the meeting, Wixbio actively discussed with a number of experts and scholars some of the dilemmas and future development directions faced by cutting-edge animal medicine technologies. At the same time, in-depth cooperation and exchanges with PHARMACINDUSTRIA company have actively discussed the current status of the use of avian vaccines in China, Russia, Kazakhstan, and Belarus, and the differentiation of detection technologies and methods for avian diseases between different countries. A series of cooperation intentions have been reached and a complete success has been achieved. Wixbio fully implements the new development concept, comprehensively integrates various resources, infuses new impetus into promoting the development of productivity, and deeply promotes the globalization of the animal pharmaceutical industry and the internationalization of scientific and technological innovation layout. --- On June 24, 2023, WIXBIO participated in the International Livestock Exhibition in Moscow. During this exhibition, WIXBIO presented its latest innovations and technical services: Innovative Vaccine Showcase: A number of highly effective vaccines for poultry, livestock, pets, and aquatic products were presented. These vaccines were developed using advanced biotechnology and can significantly improve animals' immunity. International Cooperation Platform: The newly established ChinaEurope Joint Laboratory was introduced, which will strengthen cross-border scientific research cooperation to tackle poultry diseases. Comprehensive testing services: WIXBIO's professional veterinary team provided a full range of disease diagnostic and testing services, from pathogen identification to disease prevention and control, providing customers with one-stop solutions. Exhibition Experience Through this exhibition, WIXBIO not only showed the world its leading position in the field of animal vaccines but also had in-depth exchanges with many industry experts and potential customers and established new cooperative relationships. WIXBIO's products and services have been widely recognized, and the brand's international influence has been further enhanced. Future Outlook Looking ahead, WIXBIO will continue to devote itself to technological innovation and introduce more efficient and environmentally friendly vaccine products. It will also strengthen cooperation with global partners to promote the development of the livestock industry in a more sustainable and intelligent direction. We look forward to continuing to contribute to the development of the global livestock industry in the future. --- In November 2023, a WIXBIO delegation went to Vietnam for a three-day study visit and signed a strategic cooperation agreement with CNC, a well-known local company. The purpose of the visit was to gain an in-depth understanding of the Vietnamese market's needs, explore opportunities for cooperation, and promote in-depth cooperation between the two sides in the field of animal vaccines and veterinary medicines. Highlights of the visit MARKET RESEARCH: The WIXBIO delegation first conducted detailed research on Vietnam's livestock market to understand the local farming industry's current development status, market demand, and challenges. Enterprise Visit: The delegation visited CNC's production base and R&D center and learned more about CNC's technology and facilities for producing animal vaccines and veterinary medicines. Technical exchange: WIXBIO's technical team had an in-depth technical exchange with CNC's R&D staff, sharing their experiences in vaccine R&D, quality control, and production processes. Cooperation negotiation: Both parties discussed future cooperation in the Vietnam market in detail and reached a series of consensuses. WIXBIO will provide advanced technology and product support, while CNC will be responsible for localized production and marketing. Signing Ceremony On the last day of the study visit, WIXBIO and CNC held a formal signing ceremony to sign the strategic cooperation agreement. According to the content of the agreement, both parties will cooperate in the following areas: Product introduction: WIXBIO will provide CNC with the latest animal vaccine and veterinary medicine products to meet the Vietnamese market's demand. Technology transfer: WIXBIO will assist CNC in upgrading its... --- You may hesitate whether to vaccinate your cat before spaying it. Of course, the choice lies with you, but we still recommend that your cat can remove their uterus and ovaries after vaccination. This will greatly reduce the risk of your cat contracting the disease so that your cat can establish a perfect immune system and recover quickly after the operation. This guide is designed to help you understand the necessity of spaying a cat and vaccination to help your cat stay away from disease and grow up healthy. Why do you need to spay a cat? Neutering a female cat refers to the surgery of removing the ovaries and uterus so that they cannot reproduce offspring. Spaying has many benefits for the health and life of female cats. Avoid trouble during estrus Female cats are in estrus from spring to autumn every year. During estrus, female cats become irritable and make noises to attract other male cats. The male cats fight and roar for the female cats, affecting the lives of residents. If female cats are spayed, their temperament can be made gentle. Avoid uterine and breast diseases Female cats that are not sterilized may have various diseases, such as uterine pus accumulation and breast tumors. These diseases can cause the female cat's fertility and resistance to decline and endanger its life. Sterilization surgery can avoid the occurrence of these uterine and breast diseases. Improve life expectancy and health A female cat without sterilization can give birth to more... --- As the fall and winter months approach, the flu is a concern. Many people know that the flu doesn't just affect humans but can also spread to birds and other animals. In particular, avian flu and swine flu are often of public concern. So, can the standard flu vaccine for birds and other animals prevent swine flu? Today, we'll look at this question and walk you through some of the basics of swine flu and the flu vaccine. Types of Flu Vaccines First, we need to understand the types of flu vaccines. There are two main categories of flu vaccines: human and veterinary. Human vaccines are designed to prevent humans from contracting the influenza virus. In contrast, veterinary vaccines avoid influenza in animals such as pigs, cows, sheep, chickens, and ducks. Veterinary vaccines are further categorized into vaccines for different animal species. For example, the avian influenza vaccine given to chickens mainly prevents chickens from contracting the avian flu virus. In contrast, the swine influenza vaccine given to pigs prevents pigs from contracting the swine influenza virus. Difference between swine flu and avian flu Although both swine influenza and avian influenza belong to the influenza virus category, they have significant differences in terms of antigenicity, genetic composition, and infection characteristics. An influenza virus that causes swine flu called H1N1 initially spread among pigs, hence the name "swine flu. " 2009 saw the mutation of this virus and its large-scale spread among humans, resulting in a global pandemic, commonly referred to... --- In modern society, more and more people have cats, and cats have become close companions in our lives. They are lively and cute and can always bring us laughter and comfort inadvertently. However, as a cat owner, have you ever considered whether indoor cats need vaccination? The answer is yes. Although domestic cats rarely go outside, they may still be exposed to pathogens through various means. For example, the owner's clothes and shoes may carry viruses and bacteria from outside, and small animals in the home (e. g. , mice, insects) may also become disease transmitters. In addition, some diseases are highly threatening to cats and may even be life-threatening once infected. Therefore, vaccination is essential for the health and safety of cats. Next, let's take a closer look at why indoor cats also need vaccinations and what to do to take care of their health. The Need for Indoor Cat Vaccinations Risks to Indoor Cats Even cats that live at home are not entirely protected from outside viruses. People in the house may bring germs back home if they go out, or the cat may be exposed to airborne pathogens through windows, balconies, and other places. Therefore, vaccination is the most effective way to prevent cats from being exposed to these invisible viruses. In addition, although some domestic cats do not come into direct contact with other animals, their immune systems may also gradually decline with time and age. Therefore, regular vaccinations can help cats maintain immunity against potential... --- Vaccinating your dog is essential in ensuring their health and well-being. Not only do vaccines prevent a wide range of potentially fatal diseases, but they also boost your dog's immune system. Vaccinating your dog is essential in protecting them from disease, but how do you care for them after vaccination to help them recover better? Some precautions after vaccination become very important. Have you learned about them in detail? Today, we will discuss the dos and don'ts after dog vaccinations. Here are some easy-to-understand "do's" and "don't's" for you. What to do after dog vaccination? Observe Your Dog's Physical Reactions After your dog receives its vaccinations, paying close attention to any changes in its physical condition is essential. It's normal for dogs to show mild discomfort after vaccination, such as slight swelling at the injection site, tiredness, or a reduced appetite. These reactions are usually temporary and should subside within a day or two. However, if these symptoms persist for a more extended period or worsen, you should take your dog to the vet for a check-up. Provide a Comfortable Resting Environment Vaccination may leave your dog tired or unwell, so it's essential to provide a quiet, warm space for them to rest. Avoid intense activity or stress, as adequate rest will help the immune system function better and speed up recovery. Offer Light and Easy-to-Digest Food If your dog loses its appetite after the vaccination, don't force it to eat. Instead, offer easy-to-digest food such as wet dog food... --- In September 2023, WIXBIO welcomed a delegation of agents from Pakistan, who paid a two-day visit to the company's vaccine and veterinary drug plants. The purpose of the visit was to gain an in-depth understanding of WIXBIO's R&D strength, production process, and quality control system and to explore further opportunities for cooperation between the two sides in the field of vaccines and veterinary drugs. Highlights of the visit R&D center visit: The delegation first visited WIXBIO's R&D center and learned in detail about the company's latest progress in vaccine R&D, technological innovation, and international cooperation. They appreciated WIXBIO's leading position in the field of biotechnology. Production Line Inspection: Afterwards, the delegation visited WIXBIO's modernized vaccine and veterinary medicine production line and learned about the whole process, from raw material procurement to finished product packaging. The delegation was impressed by the strict production standards and advanced production equipment. Quality Control Laboratory: In the Quality Control Laboratory, WIXBIO's technical team demonstrated the comprehensive quality testing process to ensure the safety and efficacy of each batch of products. The delegation highly praised WIXBIO's quality management system. Negotiation on cooperation: Finally, both parties had an in-depth negotiation on future cooperation in the Pakistani market. WIXBIO proposed customized solutions for the Pakistani market's characteristics and discussed the specific cooperation mode and timetable. Customer Feedback The Pakistani agent delegation highly recognized WIXBIO's R&D capability, production technology, and quality control system. They believe that WIXBIO's products and services fully meet the needs of the Pakistani market and... --- In June 2024, Dr. Essam, the CEO of DWA PHARMA FOR PHARMACEUTICAL INDUSTRIES AND COSMETICS COMPANY from Egypt, was invited to visit WIXBIO's animal vaccine manufacturing facility. During his visit, Dr. Essam toured WIXBIO's core production facility and cutting-edge research institute, where he gained valuable insights into the company's advanced manufacturing processes and innovative vaccine development. Factory Tour: A Closer Look at Production Excellence Dr. Essam was given a comprehensive tour of WIXBIO's state-of-the-art manufacturing facility. The focus was on the company's GMP certification and adherence to international quality standards. WIXBIO's rigorous compliance with global pharmaceutical and vaccine manufacturing regulations reassured Dr. Essam of the company's commitment to producing high-quality, safe, and effective animal vaccines. High Standards in Production Environment and Raw Material Control One critical point of interest for Dr. Essam was WIXBIO's controlled production environment. He was impressed by the company's stringent sterile conditions and management of animal-derived raw materials, which ensured that all production processes were free from contamination. Dr. Essam appreciated the level of detail and care taken to maintain the highest standards of hygiene and safety throughout the manufacturing process, which are critical to ensuring the quality and safety of animal vaccines. R&D Institute: Innovation at the Heart of Vaccine Development A highlight of Dr. Essam's visit was his tour of WIXBIO's research institute, where the company focuses on developing cutting-edge animal vaccines. Dr. Essam was impressed with the scientific innovation and rigorous testing protocols for vaccine development. The institute's advanced laboratories and skilled team... --- In October 2023, WIXBIO welcomed an official visit from Dr Geoffery, Managing Director, and Dr Nicky, Sales Director of Atlantis Pharmaceuticals from Kenya. This visit is an essential step for both parties to strengthen their partnership further and is crucial for WIXBIO to deepen its presence in the African market. High-level exchanges to deepen cooperation cooperation intention During the visit, Dr. Geoffery and Dr. Nicky had a detailed understanding of WIXBIO's background, core technology, and product lines and visited WIXBIO's core production plant, where WIXBIO's technical team showed the guests the company's innovative capability and production process in the field of animal vaccines, and Dr Geoffery and Dr Nicky expressed their appreciation for WIXBIO's efforts in vaccine research and development, vaccine production and vaccine manufacturing. Dr. Geoffery and Dr. Nicky highly appreciated WIXBIO's strict management and professionalism in vaccine R&D, production process, and quality control. Impressive factory tour During the visit Dr. Geoffery and Dr. Nicky were impressed by WIXBIO's advanced production equipment and high-standard production environment, which strictly follows the GMP certification process to ensure that each batch of vaccine products meets international quality standards. At every stage of the production line, WIXBIO carries out strict quality testing, from the procurement of raw materials to the delivery of final products, to ensure the safety and effectiveness of the products. Especially in vaccine research and development WIXBIO's technical team demonstrated the company's research results and independent innovation ability. WIXBIO not only focuses on routine vaccine research and development but also... --- In March 2024, WIXBIO welcomed a delegation from Alaq, Al-Shaheen Co. for Trading of Veterinary Medicines, Pesticides, and Agriculture Supplies Ltd (from now on referred to as Alaq, Al-Shaheen Co. ). (from now on referred to as Alaq, Al-Shaheen Company). The delegation, which included the company's Managing Director, Dr. Osamah, and officials from the Ministry of Agriculture, Dr. Hasan and Dr. Rabab, visited the company to conduct a factory inspection of WIXBIO's production facilities and discuss future strategic cooperation. As an essential trading company of animal vaccines, pesticides, and agricultural supplies in Iraq and the Middle East, Alaq, Al-Shaheen has long been committed to providing high-quality products and services to the local farming industry. The visit was the first in-depth exchange between the two parties. It signaled significant progress in WIXBIO's strategic goal of expanding into international markets, especially in the Middle East and North Africa. In-depth exchanges demonstrate WIXBIO's strength. On the visit day, WIXBIO warmly received the delegation from Alaq, Al-Shaheen, and arranged a detailed tour of the company. Dr Osamah and the team visited WIXBIO's R&D laboratory and production plant, focusing on the company's technological strengths in animal vaccine research and development, production, and quality control. The WIXBIO technical team explained every aspect of vaccine production in detail. The team explained in detail every essential step of vaccine production, from raw material procurement, production formulation, R&D testing, and final quality inspection, to ensure that every batch of vaccine meets international standards. Dr. Hasan and Dr. Rabab also... --- In May 2024, Nguyen Minh, Chairman of Vietnam CNC Veterinary Production and Trading Joint Stock Company (AniVacC Jsc. ), and his delegation visited WIXBIO. They aimed to exchange in-depth information on the current trends of epidemic diseases, product R&D and innovation, technology transfer, exchange of talents, and critical technological research and development and lay a solid foundation for future strategic cooperation. In-depth discussion on cooperation and development During the visit, Chairman Ruan Minh and the CNC team spoke with WIXBIO senior management several times. The two sides focused on the current disease prevention and control situation, especially the demand for preventing and controlling swine foot-and-mouth disease, avian influenza H5+H9, and duck Tambucus. They shared the latest progress of their respective vaccine R&D, technological innovation, and product transformation. WIXBIO introduced its strengths in vaccine R&D and production, especially its leading ability in customized vaccine production and technical support. Chairman Nguyen Minh said CNC has always been committed to improving agriculture and animal disease prevention in Vietnam and neighboring areas. This visit gave CNC a better understanding of WIXBIO's technical strength and R&D capability and opened up more possibilities for the two sides in technical cooperation and product promotion. Signing a strategic cooperation agreement to promote technological breakthroughs jointly Both parties reached a consensus during the discussion and plan to sign a comprehensive strategic cooperation agreement shortly to strengthen further the cooperation in vaccine R&D, technical support, and marketing. It is expected that by 2025, CNC will successfully obtain import registration certificates... --- You must be careful if your dog often goes out to play, has frequent contact with wild animals, or drinks unclean water. Your dog may be infected with leptospirosis. This article aims to help you understand leptospirosis and provide your dog with a lepto vaccination program to help your dog's immune system activate quickly and effectively resist leptospirosis. What is leptospirosis? Leptospirosis is a zoonotic infectious disease caused by leptospirosis bacteria. Wild animals such as pigs, dogs, cats, and rats may be infected with leptospirosis. The most common hosts are rodents, especially wild rats (mice, possums, etc. ). How are dogs infected? Mice and other rodents mainly carry leptospirosis bacteria but can also be taken by mammals such as pigs, dogs, and humans. When the urine of infected animals is excreted and contaminates water and soil, leptospirosis will grow exponentially in a suitable environment (especially in a warm and humid environment). When the mucous membranes of the dog's damaged skin, eyes, mouth, nasal cavity, or vagina come into contact with contaminated water or soil, or when the dog preys on infected small animals, it may be infected with leptospirosis. After hurricanes, heavy rains, or floods, bacteria multiply and spread rapidly, and the risk of infection in humans and animals increases exponentially. What are the symptoms of dogs after contracting leptospirosis? The usual symptoms of dogs after infection are loss of appetite, drowsiness, and high fever. Severe symptoms of dogs after infection： Acute kidney injury: vomiting, diarrhea, blood in the stool,... --- ---