AI H5N1 Inactivated Vaccine Description
This inactivated avian influenza vaccine is formulated with two reassortant H5 subtype strains:
- Re-6 (H5N1) – high antigenic match to earlier circulating H5 clades
- Re-8 (H5N1) – improved coverage for evolving H5 variants
The combination provides enhanced cross-protection against multiple H5 avian influenza strains, making it suitable for regions with complex or shifting epidemiological profiles.
Avian influenza (H5 subtype) is a highly contagious and often high-pathogenic disease, causing severe respiratory symptoms, systemic infection, high mortality, and significant economic losses in poultry production.
This oil-emulsion inactivated vaccine induces strong humoral immunity, forming a protective barrier at the population level. It is widely used in routine vaccination programs and government immunization campaigns.
The vaccine is suitable for chickens, ducks, and geese, offering flexible application across different poultry production systems.
Immunization Program
- Chickens:
- Primary vaccination at 2–5 weeks
- Booster depending on local program and risk level
- Ducks & Geese:
- Primary vaccination at 2–5 weeks
- Booster recommended in high-risk or endemic areas
- Commonly integrated into regional avian influenza control programs
Dosage & Administration
- Route:
- Intramuscular injection (chest)
- Subcutaneous injection (neck)
Dosage:
- Chickens:
- 2–5 weeks: 0.3 mL
- 5 weeks: 0.5 mL
- Ducks:
- 2–5 weeks: 0.5 mL
- 5 weeks: 1.0 mL
- Geese:
- 2–5 weeks: 0.5 mL
- 5 weeks: 1.5 mL
Composition
- Inactivated H5N1 strain Re-6: HA titer ≥ 1:512 (pre-inactivation)
- Inactivated H5N1 strain Re-8: HA titer ≥ 1:256 (pre-inactivation)
Product Characteristics
- Appearance: Milky white emulsion
- Stable oil-adjuvanted formulation
- Strong and consistent immune response
Safety & Adverse Reactions
- Generally no visible adverse reactions
- Safe for use in healthy poultry
Precautions
- Do NOT use in:
- Birds infected with avian influenza
- Birds in poor health condition
- Do not freeze
- Inspect before use:
- Do not use if damaged, contaminated, or demulsified
- Before use:
- Bring to room temperature
- Shake thoroughly
- Use aseptic techniques:
- Replace needles frequently (preferably one per bird)
- After opening:
- Use within the same day
- Withdrawal period:
- Do not use within 28 days before slaughter
- Dispose of vaccine materials safely
Packaging & Specification
- Specifications:
- 250 mL/bottle
- 500 mL/bottle
- Packaging:
- 20 bottles/carton
- 40 bottles/carton
Storage & Shelf Life
- Storage: 2–8°C
- Do NOT freeze
- Shelf Life: 24 months
