AI H5 Inactivated Vaccine Description
This inactivated bivalent avian influenza vaccine is formulated with two reassortant H5 subtype strains:
- H5-Re13 (H5N6) – targeting clade 2.3.4.4h
- H5-Re14 (H5N8) – targeting clade 2.3.4.4b
These strains are selected to provide broad cross-protection against currently circulating H5 avian influenza variants, which are responsible for significant outbreaks in poultry worldwide.
Avian influenza (AI) is a highly contagious viral disease causing severe respiratory distress, decreased egg production, high mortality, and major economic losses. Effective vaccination is critical for disease control, especially in endemic and high-risk regions.
This oil-emulsion inactivated vaccine induces strong and long-lasting humoral immunity, with protection developing 14 days post-vaccination.
- Chickens: Protection lasts up to 6 months
- Ducks & Geese: Require booster vaccination after 3 weeks, with protection lasting 4 months
The vaccine is suitable for commercial poultry farms, breeder operations, and integrated production systems, particularly where H5 subtype variants are prevalent.
Immunization Program
- Chickens:
- Single vaccination
- Immunity duration: ~6 months
- Ducks & Geese:
- Primary vaccination
- Booster after 3 weeks
- Immunity duration: ~4 months
Dosage & Administration
- Route:
- Intramuscular (chest)
- Subcutaneous (neck)
Dosage:
- Chickens:
- 2–5 weeks: 0.3 mL
- 5 weeks: 0.5 mL
- Ducks & Geese:
- 2–5 weeks: 0.5 mL
- 5 weeks: 1.0 mL
Composition
- Inactivated H5N6 (H5-Re13): HA titer ≥ 1:256 (pre-inactivation)
- Inactivated H5N8 (H5-Re14): HA titer ≥ 1:256 (pre-inactivation)
Product Characteristics
- Appearance: Milky white uniform emulsion
- Stable oil-adjuvanted formulation
- Strong immune response induction
Safety & Adverse Reactions
- No significant adverse reactions observed
- Safe for use in healthy poultry
Precautions
- Do NOT use in:
- Poultry infected with avian influenza
- Birds in poor health condition
- Do not freeze
- Inspect before use:
- Do not use if damaged, contaminated, or demulsified
- Before use:
- Bring to room temperature
- Shake thoroughly
- Use aseptic techniques:
- Replace needles regularly (preferably one needle per bird)
- After opening:
- Use within the same day
- Withdrawal period:
- Do not use within 28 days before slaughter
- Dispose of vaccine materials safely
Packaging & Specification
- Specification: 500 mL/bottle
- Packaging: 20 bottles/carton
Storage & Shelf Life
- Storage: 2–8°C
- Do NOT freeze
- Shelf Life: 24 months
